Evidence map›Paper›PMID 18463207›Full record

ArticleJournal of clinical microbiology2008

Rapid identification of penicillin and macrolide resistance genes and simultaneous quantification of Streptococcus pneumoniae in purulent sputum samples by use of a novel real-time multiplex PCR assay.

Kazuko Y Fukushima, Katsunori Yanagihara, Yoichi Hirakata, Kazuyuki Sugahara, Yoshitomo Morinaga, Shigeru Kohno, Shimeru Kamihira

Registry-linked trialOpen access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00867841 (A Polymerase Chain Reaction-based Method to Improve Antibiotic Prescribing for Children and Adolescents With Community-Acquired Pneumonia - a Pilot Study), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00867841 withdrawnnot on this map

A Polymerase Chain Reaction-based Method to Improve Antibiotic Prescribing for Children and Adolescents With Community-Acquired Pneumonia - a Pilot Study

TypeobservationalSponsorChildren's Hospital of Eastern OntarioEnrolled0ConditionsPneumoniaArmsnasopharyngeal swab
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kazuko Y FukushimaDepartment of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki City 852-8501, Japan.
Katsunori Yanagihara
Yoichi Hirakata
Kazuyuki Sugahara
Yoshitomo Morinaga
Shigeru Kohno
Shimeru Kamihira
Nagasaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated a real-time quantitative PCR combined with a multiplex PCR assay for the quantification of Streptococcus pneumoniae and the simultaneous detection of drug-resistant genes by gel-based PCR, using purulent sputum samples. This assay correctly quantified S. pneumoniae and identified their penicillin and erythromycin susceptibilities directly from samples within 3 h.

Indexed as

Anti-Bacterial AgentsColony Count, MicrobialDNA, BacterialDrug Resistance, BacterialElectrophoresis, Agar GelHumansMacrolidesMicrobial Sensitivity TestsPenicillinsPneumococcal InfectionsPolymerase Chain ReactionSputumStreptococcus pneumoniaeSuppurationAnti-Bacterial AgentsDNA, BacterialMacrolidesPenicillins

Identifiers

PMID18463207
PMCPMC2446912
OpenAlexW2143477631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.