Trial reportClinical infectious diseases : an official publication of the Infectious Diseases Society of America2008
Impact of lactoferrin supplementation on growth and prevalence of Giardia colonization in children.
Trial report in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 85 citations in OpenAlex.
- Effects of bovine colostrum on recurrent respiratory tract infections and diarrhea in children.Medicine · 2016Trial
- Growth and tolerance of formula with lactoferrin in infants through one year of age: double-blind, randomized, controlled trial.BMC pediatrics · 2015Trial
- Trial
- Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children.The Journal of pediatrics · 2013Trial
- Protection against diarrhea associated with Giardia intestinalis Is lost with multi-nutrient supplementation: a study in Tanzanian children.PLoS neglected tropical diseases · 2011Trial
- Pharmacologic and Adjunct Therapies for Pediatric Gastroenteritis.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Selected Protective Mechanisms of Human Milk Against Intestinal Protozoal Infections in Infants.Current issues in molecular biology · 2025Review
- Bactericidal/Permeability-Increasing Protein (BPI), a Novel Antimicrobial Molecule in Human Breast Milk with Immune Potential.Microorganisms · 2025Article
- Lactoferrin Supplementation in Preventing and Protecting from SARS-CoV-2 Infection: Is There Any Role in General and Special Populations? An Updated Review of Literature.International journal of molecular sciences · 2024Review
- Characterization of recombinant human lactoferrin expressed inThe Analyst · 2024Article
- Clinical research review: usefulness of bovine lactoferrin in child health.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Review
- Lactoferrin for the postoperative management of term neonates after gastrointestinal surgery.The Cochrane database of systematic reviews · 2023Review
- Article
- Effect of lactoferrin in oral nutrition supplement (ONS) towards IL-6 and IL-10 in failure to thrive children with infection.F1000Research · 2023Article
- Human Milk Microbiome and Microbiome-Related Products: Potential Modulators of Infant Growth.Nutrients · 2022Review
- Activity of Apo-Lactoferrin on Pathogenic Protozoa.Pharmaceutics · 2022Review
- Lactoferrin: Cytokine Modulation and Application in Clinical Practice.Journal of clinical medicine · 2021Review
- The need to study human milk as a biological system.The American journal of clinical nutrition · 2021Article
- Human milk immunomodulatory proteins are related to development of infant body composition during the first year of lactation.Pediatric research · 2021Observational
- Bovine Colostrum: Its Constituents and Uses.Nutrients · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
We conducted a randomized, double-blind, placebo-controlled trial comparing supplementation with bovine lactoferrin versus placebo for the prevention of diarrhea in children. Comparison of overall diarrhea incidence and prevalence rates found no significant difference between the 2 groups. However, there was a lower prevalence of colonization with Giardia species and better growth among children in the lactoferrin group.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.