Evidence map›Paper›PMID 18462090›Full record

ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America2008

Pathogenesis of methicillin-resistant Staphylococcus aureus infection.

Rachel J Gordon, Franklin D Lowy

Abstract readReview
In one paragraph

Review in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 393 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
393citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

393 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Risk factors for methicillin-resistantThe Journal of international medical research · 2022
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. The global epidemiology of MRSA.JAC-antimicrobial resistance · 2026
    Review
  8. Article
  9. Article
  10. Metabolic reprogramming promotesMicrobiology (Reading, England) · 2026
    Article
  11. Article
  12. Review
  13. Unraveling the mouse model ofMicrobiology spectrum · 2026
    Article
  14. Review
  15. Review
  16. Animals : an open access journal from MDPI · 2026
    Review
  17. Article
  18. Article
  19. Review
  20. Article

333 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rachel J GordonDivision of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Franklin D Lowy

Funding

Ventricular Assist Devices: Bleeding/Thrombosis &TherapyP50HL077096 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LAZAR, DANIEL · 2005 to 2008
$13.4M
Social Networks of S. aureus Carriage Among Drug UsersR01DA015018 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOWY, FRANKLIN D · 2002 to 2006
$3.1M
Research: Antimicrobial Resistance (RMI)P20RR020616 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LARSON, ELAINE LUCILLE · 2004 to 2006
$1.7M
Pathogenesis & epidemiology of S epidermidis ventricular assist device infectionsK08AI072043 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GORDON, RACHEL J. · 2007 to 2011
$622k
NCRR NIH HHS P20 RR020616NHLBI NIH HHS HL077096-01NHLBI NIH HHS P50 HL077096NIAID NIH HHS 1K08AI072043-01A1NIAID NIH HHS K08 AI072043NIDA NIH HHS DA-15018NIDA NIH HHS R01 DA015018PHS HHS CCR223380
6 · The paper itself

Abstract

Staphylococcus aureus is a versatile pathogen capable of causing a wide range of human diseases. However, the role of different virulence factors in the development of staphylococcal infections remains incompletely understood. Some clonal types are well equipped to cause disease across the globe, whereas others are facile at causing disease among community members. In this review, general aspects of staphylococcal pathogenesis are addressed, with emphasis on methicillin-resistant strains. Although methicillin-resistant S. aureus (MRSA) strains are not necessarily more virulent than methicillin-sensitive S. aureus strains, some MRSA strains contain factors or genetic backgrounds that may enhance their virulence or may enable them to cause particular clinical syndromes. We examine these pathogenic factors.

Indexed as

Methicillin ResistanceHumansStaphylococcal InfectionsStaphylococcus aureusVirulenceVirulence FactorsVirulence Factors

Identifiers

PMID18462090
PMCPMC2474459

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.