ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2008
Elucidating chromatin and nuclear domain architecture with electron spectroscopic imaging.
Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Single-Cell, High-Content Microscopy Analysis of BK Polyomavirus Infection.Microbiology spectrum · 2023Article
- A proposed unified interphase nucleus chromosome structure: Preliminary preponderance of evidence.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Regulation of Chromatin Organization in Cell Stemness: The Emerging Role of Long Non-coding RNAs.Stem cell reviews and reports · 2021Review
- DNA methylation is dispensable for changes in global chromatin architecture but required for chromocentre formation in early stem cell differentiation.Chromosoma · 2017Article
- Gene functioning and storage within a folded genome.Cellular & molecular biology letters · 2017Review
- Coming to terms with chromatin structure.Chromosoma · 2016Review
- Correlative fluorescence and EFTEM imaging of the organized components of the mammalian nucleus.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Modulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations.PloS one · 2013Article
- A fractal model for nuclear organization: current evidence and biological implications.Nucleic acids research · 2012Review
- Towards an atlas of mammalian cell ultrastructure by cryo soft X-ray tomography.Journal of structural biology · 2012Article
- Innate structure of DNA foci restricts the mixing of DNA from different chromosome territories.PloS one · 2011Article
- Spatial Organization and Dynamics of Transcription Elongation and Pre-mRNA Processing in Live Cells.Genetics research international · 2011Article
- Nonlinear optical imaging and Raman microspectrometry of the cell nucleus throughout the cell cycle.Biophysical journal · 2010Article
- Global chromatin architecture reflects pluripotency and lineage commitment in the early mouse embryo.PloS one · 2010Article
- Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis.Genome research · 2010Article
- Nuclear envelope-limited chromatin sheets (ELCS) and heterochromatin higher order structure.Chromosoma · 2009Review
- Determining molecular mass distributions and compositions of functionalized dendrimer nanoparticles.Nanomedicine (London, England) · 2009Article
- Single molecule localization microscopy of the distribution of chromatin using Hoechst and DAPI fluorescent probes.Nucleus (Austin, Tex.)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electron microscopy has been the 'gold standard' of spatial resolution for studying the structure of the cell nucleus. Electron spectroscopic imaging (ESI) offers advantages over conventional transmission electron microscopy by eliminating the need for heavy-atom contrast agents. ESI also provides mass-dependent and element-specific information at high resolution, permitting the distinguishing of structures that are primarily composed of protein, DNA, or RNA. The technique can be applied to understand the structural consequences of epigenetic modifications, such as modified histones, on chromatin fiber morphology. ESI can also be applied to elucidate the multifunctional behavior of subnuclear 'organelles' such as the nucleolus and promyelocytic leukemia nuclear bodies.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.