ArticleNucleic acids research2008
ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data.
Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Coherent pathway enrichment estimation by modeling inter-pathway dependencies using regularized regression.Bioinformatics (Oxford, England) · 2023Article
- Application of Transcriptomics for Predicting Protein Interaction Networks, Drug Targets and Drug Candidates.Frontiers in medical technology · 2022Review
- Haploinsufficiency of X-linked intellectual disability gene CASK induces post-transcriptional changes in synaptic and cellular metabolic pathways.Experimental neurology · 2020Article
- A Cancer Gene Module Mining Method Based on Bio-Network of Multi-Omics Gene Groups.Frontiers in oncology · 2020Article
- AG3 (Bethesda, Md.) · 2018Article
- Molecular characterization of tsetse's proboscis and its response to Trypanosoma congolense infection.PLoS neglected tropical diseases · 2017Article
- A comparative study on endovascular treatment of (sub)acute critical limb ischemia: mechanical thrombectomy vs thrombolysis.Drug design, development and therapy · 2017Article
- Mitochondrial-Nuclear Interactions Mediate Sex-Specific Transcriptional Profiles in Drosophila.Genetics · 2016Article
- The Genetic Basis for Variation in Sensitivity to Lead Toxicity in Drosophila melanogaster.Environmental health perspectives · 2016Article
- SOX7 co-regulates Wnt/β-catenin signaling with Axin-2: both expressed at low levels in breast cancer.Scientific reports · 2016Article
- Insights into the trypanosome-host interactions revealed through transcriptomic analysis of parasitized tsetse fly salivary glands.PLoS neglected tropical diseases · 2014Article
- A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology.PLoS genetics · 2014Article
- Neuron-specific protein interactions of Drosophila CASK-β are revealed by mass spectrometry.Frontiers in molecular neuroscience · 2014Article
- Article
- Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers.Oncotarget · 2013Article
- Investigating the concordance of Gene Ontology terms reveals the intra- and inter-platform reproducibility of enrichment analysis.BMC bioinformatics · 2013Article
- A role for RNA post-transcriptional regulation in satellite cell activation.Skeletal muscle · 2012Article
- GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics.Nucleic acids research · 2012Article
- Human adipose tissue macrophages display activation of cancer-related pathways.The Journal of biological chemistry · 2012Article
- Annotation concept synthesis and enrichment analysis: a logic-based approach to the interpretation of high-throughput experiments.Bioinformatics (Oxford, England) · 2011Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of 'complex functions'. A 'Complex function' is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. ProfCom provides a user friendly dialog-driven web page submission available for several model organisms and supports most available gene identifiers. In addition, the web service interface allows the submission of any kind of annotation data. ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/.
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Registered trials
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