ArticleJournal of virology1991
Identification of a common viral integration region in Cas-Br-E murine leukemia virus-induced non-T-, non-B-cell lymphomas.
Article in Journal of virology, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
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- The role of translation initiation regulation in haematopoiesis.Comparative and functional genomics · 2012Article
- Drug-mediated inhibition of Fli-1 for the treatment of leukemia.Blood cancer journal · 2012Article
- Sox4 cooperates with Evi1 in AKXD-23 myeloid tumors via transactivation of proviral LTR.Blood · 2006Article
- Animal models of acute myelogenous leukaemia - development, application and future perspectives.Leukemia · 2005Review
- Mutational effects of retrovirus insertion on the genome of V79 cells by an attenuated retrovirus vector: implications for gene therapy.Gene therapy · 2003Article
- Article
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- Review
- Ets and retroviruses - transduction and activation of members of the Ets oncogene family in viral oncogenesis.Oncogene · 2000Review
- Genetic heterogeneity in acute myeloid leukemia: maximizing information flow from MuLV mutagenesis studies.Leukemia · 2000Review
- The GATA-1 and Spi-1 transcriptional factors bind to a GATA/EBS dual element in the Fli-1 exon 1.Oncogene · 1999Article
- Oncogene activation in myeloid leukemias by Graffi murine leukemia virus proviral integration.Journal of virology · 1999Article
- Members of the GATA family of transcription factors bind to the U3 region of Cas-Br-E and graffi retroviruses and transactivate their expression.Journal of virology · 1998Article
- Differentiation arrest and stromal cell-independent growth of murine erythroleukemia cells are associated with elevated expression of ets-related genes but not with mutation of p53.Molecular and cellular biology · 1993Article
- Genetic mapping of opioid binding protein gene(s) to mouse chromosome 9.Mammalian genome : official journal of the International Mammalian Genome Society · 1993Article
- Mouse chromosome 9.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- Targeted integration of adeno-associated virus (AAV) into human chromosome 19.The EMBO journal · 1991Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Cas-Br-E murine leukemia virus is a nondefective retrovirus that induces non-T-, non-B-cell lymphomas in susceptible NIH/Swiss mice. By using a DNA probe derived from Cas-Br-E provirus-flanking sequences, we identified a DNA region, originally called Sic-1, rearranged in 16 of 24 tumors analyzed (67%). All proviruses were integrated in a DNA segment smaller than 100 bp and were in the same 5'-to-3' orientation. Ecotropic as well as mink cell focus-forming virus types were found integrated in that specific DNA region. On the basis of Southern blot analysis of somatic cell hybrids and progeny of an interspecies backcross, the Sic-1 region was localized on mouse chromosome 9 near the previously described proto-oncogenes or common viral integration sites: Ets-1, Cbl-2, Tpl-1, and Fli-1. Restriction map analysis shows that this region is identical to the Fli-1 locus identified in Friend murine leukemia virus-induced erythroleukemia cell lines and thus may contain sequences also responsible for the development of mouse non-T-, non-B-cell lymphomas.
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