Trial reportBMC health services research2008
Multidisciplinary collaborative care for depressive disorder in the occupational health setting: design of a randomised controlled trial and cost-effectiveness study.
Trial report in BMC health services research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 7 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effectiveness of the Participatory Approach on Return-to-Work of Sick-Listed Workers: A Systematic Review and Meta-analysis.Journal of occupational rehabilitation · 2026Pooled it
- Effectiveness of Workplace Interventions in Return-to-Work for Musculoskeletal, Pain-Related and Mental Health Conditions: An Update of the Evidence and Messages for Practitioners.Journal of occupational rehabilitation · 2018Pooled it
- Workplace interventions to prevent work disability in workers on sick leave.The Cochrane database of systematic reviews · 2015Pooled it
- Pooled it
- Cost-effectiveness of collaborative care for the treatment of depressive disorders in primary care: a systematic review.PloS one · 2015Pooled it
- Interventions to facilitate return to work in adults with adjustment disorders.The Cochrane database of systematic reviews · 2012Pooled it
- Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012Pooled it
- Cost-utility analysis of a collaborative care intervention for major depressive disorder in an occupational healthcare setting.Journal of occupational rehabilitation · 2014Trial
- Trial
- Even the COVID-19 pandemic didn´t change anything: insights from a trend study on the cooperation of general practitioners and occupational health physicians in Germany.BMC primary care · 2026Article
- The patient-doctor relationship questionnaire (PDRQ-9). An overview of 20 years of research and a proposal for normalisation of scores. Systematic review.Frontiers in health services · 2026Review
- Stakeholders' Role and Actions in the Return-to-Work Process of Workers on Sick-Leave Due to Common Mental Disorders: A Scoping Review.Journal of occupational rehabilitation · 2020Article
- Cost-utility of collaborative care for the treatment of comorbid major depressive disorder in outpatients with chronic physical conditions. A randomized controlled trial in the general hospital setting (CC-DIM).Neuropsychiatric disease and treatment · 2017Article
- Sustaining Work Participation Across the Life Course.Journal of occupational rehabilitation · 2016Review
- Workplace Interventions to Prevent Disability from Both the Scientific and Practice Perspectives: A Comparison of Scientific Literature, Grey Literature and Stakeholder Observations.Journal of occupational rehabilitation · 2016Article
- Risk factors of recurrent sickness absence due to depression: a two-year cohort study among Japanese employees.International archives of occupational and environmental health · 2015Article
- Let's get back to work: survival analysis on the return-to-work after depression.Neuropsychiatric disease and treatment · 2013Article
- Blended E-health module on return to work embedded in collaborative occupational health care for common mental disorders: design of a cluster randomized controlled trial.Neuropsychiatric disease and treatment · 2013Article
- Article
- Predicting return to work in workers with all-cause sickness absence greater than 4 weeks: a prospective cohort study.Journal of occupational rehabilitation · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMajor depressive disorder (MDD) has major consequences for both patients and society, particularly in terms of needlessly long sick leave and reduced functioning. Although evidence-based treatments for MDD are available, they show disappointing results when implemented in daily practice. A focus on work is also lacking in the treatment of depressive disorder as well as communication of general practitioners (GPs) and other health care professionals with occupational physicians (OPs). The OP may play a more important role in the recovery of patients with MDD. Purpose of the present study is to tackle these obstacles by applying a collaborative care model, which has proven to be effective in the USA, with a focus on return to work (RTW). From a societal perspective, the (cost)effectiveness of this collaborative care treatment, as a way of transmural care, will be evaluated in depressed patients on sick leave in the occupational health setting. METHODS/
designA randomised controlled trial in which the treatment of MDD in the occupational health setting will be evaluated in the Netherlands. A transmural collaborative care model, including Problem Solving Treatment (PST), a workplace intervention, antidepressant medication and manual guided self-help will be compared with care as usual (CAU). 126 Patients with MDD on sick leave between 4 and 12 weeks will be included in the study. Care in the intervention group will be provided by a multidisciplinary team of a trained OP-care manager and a consultant psychiatrist. The treatment is separated from the sickness certification. Data will be collected by means of questionnaires at baseline and at 3, 6, 9 and 12 months after baseline. Primary outcome measure is reduction of depressive symptoms, secondary outcome measure is time to RTW, tertiary outcome measure is the cost effectiveness. DISCUSSION: The high burden of MDD and the high level of sickness absence among people with MDD contribute to the relevance of this study. The intervention is an innovative approach, with trained OPs in a new role as care managers in the treatment of MDD. If this intervention proves to be cost-effective, implementation will be very relevant for individual patients as well as for society.
trial registrationISRCTN78462860.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.