SynthesisWorld journal of surgery2008
Metabolic implications of severe burn injuries and their management: a systematic review of the literature.
Synthesis in World journal of surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Poor methodological quality and reporting standards of systematic reviews in burn care management.International wound journal · 2017Pooled it
- Safety and effectiveness of propranolol in severely burned patients: systematic review and meta-analysis.World journal of emergency surgery : WJES · 2017Pooled it
- Session Rating of Perceived Exertion Is a Valid Method to Monitor Intensity of Exercise in Adults with Acute Burn Injuries.European burn journal · 2025Article
- Update on Hypermetabolism in Pediatric Burn Patients.Seminars in plastic surgery · 2024Review
- High-dose intravenous versus low-dose oral vitamin C in burn care: potential protective effects in the severely burned: a retrospective cohort study.Annals of medicine and surgery (2012) · 2023Article
- Review
- A Reappraisal of Oxandrolone in Burn Management.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2022Review
- Application of beta-blockers in burn management.Proceedings (Baylor University. Medical Center) · 2022Article
- Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs.Journal of burn care & research : official publication of the American Burn Association · 2021Article
- Effect of Collagen Hydrolysate and Fish Oil on High-Sensitivity C-Reactive Protein and Glucose Homeostasis in Patients with severe Burn; a Randomized Clinical Trial.Archives of academic emergency medicine · 2021Article
- Long-term mental health outcomes after unintentional burns sustained during childhood: a retrospective cohort study.Burns & trauma · 2018Article
- Hip fracture risk in patients with burn injury: a retrospective cohort study in Taiwan.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Article
- Staphylococcus aureus carriage at admission predicts early-onset pneumonia after burn trauma.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Management of burns in the elderly.Annals of burns and fire disasters · 2016Article
- Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages.Scientific reports · 2016Article
- Effectiveness of resistance strength training in children and adolescents with ≥30% total body surface area: A systematic review.The South African journal of physiotherapy · 2016Article
- Major Transcriptome Changes Accompany the Growth of Pseudomonas aeruginosa in Blood from Patients with Severe Thermal Injuries.PloS one · 2016Article
- Long-term mortality among older adults with burn injury: a population-based study in Australia.Bulletin of the World Health Organization · 2015Article
- A comparison of Biobrane™ and cadaveric allograft for temporizing the acute burn wound: Cost and procedural time.Burns : journal of the International Society for Burn Injuries · 2015Article
- Physical rehabilitation of pediatric burns.Annals of burns and fire disasters · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere burn patients are some of the most challenging critically ill patients, with an extreme state of physiologic stress and an overwhelming systemic metabolic response. A major component of severe burn injury is a hypermetabolic state associated with protein losses and a significant reduction of lean body mass. The second prominent component is hyperglycemia. Reversal of the hypermetabolic response by manipulating the patient's physiologic and biochemical environment through the administration of specific nutrients, growth factors, or other agents, often in pharmacologic doses, is emerging as an essential component of the state of the art in severe burn management. The present review aims at summarizing the new treatment modalities established to reduce the catabolic burden of severe burn injuries, for which there is some evidence-based support.
methodsA systematic review of the literature was conducted. Search tools included Elsevier ScienceDirect, EMBASE.com, Medline (OVID), MedlinePlus, and PubMed. Topics searched were Nutrition and Burns, Metabolic Response and Burns, Hypermetabolism and Burns, Hyperglycemia and Burns, and several more specific topics when indicated. With a focus on the most recently published articles, abstracts were reviewed and, when found relevant, were included as references. Full text articles, whenever available, were retrieved.
resultsMany issues remain unanswered. Unfortunately, the present state of our knowledge does not allow the formulation of clear-cut guidelines. Only general trends can be outlined, and these will certainly have some practical applications but above all will dictate future research in the field.
Indexed as
Identifiers
18454355What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.