ArticleWorld journal of surgery2008
Impact of the degree of liver resection on survival for patients with multiple liver metastases from colorectal cancer.
Article in World journal of surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Clinical outcomes of parenchymal-sparing versus anatomic resection for colorectal liver metastases: a systematic review and meta-analysis.World journal of surgical oncology · 2023Pooled it
- Parenchymal-sparing versus extended hepatectomy for colorectal liver metastases: A systematic review and meta-analysis.Cancer medicine · 2019Pooled it
- Resection of colorectal liver metastases and extra-hepatic disease: a systematic review and proportional meta-analysis of survival outcomes.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2016Pooled it
- Pushing the Limits of Surgical Resection in Colorectal Liver Metastasis: How Far Can We Go?Cancers · 2023Review
- Microwave Ablation for Colorectal Liver Metastases: A Systematic Review and Pooled Oncological Analyses.Cancers · 2022Review
- Technique of vessel-skeletonized parenchyma-sparing hepatectomy for the oncological treatment of bilobar colorectal liver metastases.Langenbeck's archives of surgery · 2022Article
- Contemporary evidence on colorectal liver metastases ablation: toward a paradigm shift in locoregional treatment.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2022Article
- Laparoscopic Parenchyma-sparing Liver Resection for Colorectal Metastases.Radiology and oncology · 2018Article
- Proposal of Two Prognostic Models for the Prediction of 10-Year Survival after Liver Resection for Colorectal Metastases.HPB surgery : a world journal of hepatic, pancreatic and biliary surgery · 2018Article
- Borderline operability in hepatectomy patients is associated with higher rates of failure to rescue after severe complications.Journal of surgical oncology · 2017Article
- Parenchymal-sparing hepatectomies (PSH) for bilobar colorectal liver metastases are associated with a lower morbidity and similar oncological results: a propensity score matching analysis.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2016Article
- Parenchymal-sparing liver surgery in patients with colorectal carcinoma liver metastases.World journal of gastrointestinal surgery · 2016Review
- Anatomy of Hepatic Resectional Surgery.The Surgical clinics of North America · 2016Review
- Parenchyma-preserving hepatic resection for colorectal liver metastases.Langenbeck's archives of surgery · 2012Article
- Survival after liver resection in metastatic colorectal cancer: review and meta-analysis of prognostic factors.Clinical epidemiology · 2012Article
- Liver resection for advanced or aggressive colorectal cancer metastases in the era of effective chemotherapy: a review.International journal of clinical oncology · 2011Review
- Parenchyma-sparing hepatectomy (PSH) versus non-PSH for bilobar liver metastases of colorectal cancer.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough the degree of hepatic resection has been found to be a key aspect of tumor stimulation, the differences in clinical outcome between a massive liver resection and a less extensive resection for multiple colorectal metastases have not been well studied. The purpose of this study was to clarify the impact of the extent of liver resection on survival outcome.
methodsClinicopathologic data were available for 85 patients who were surgically treated for four or more liver metastases. Forty-nine patients who underwent a major hepatic resection were compared with patients who underwent minor hepatic resections (n = 36).
resultsAs the patients undergoing major resection were more likely to have multiple (p = 0.014) and large tumors (p = 0.021) compared to the minor-resection patients, their overall survival was worse (p = 0.046) and the disease-free rate tended to be poorer. By multivariate analysis of the cohorts, the only independent factor affecting survival was the number of liver tumors (< or =5 or > or =6; relative risk [RR] = 0.427; p = 0.014). When patients with six or more metastases were selected and analyzed, the overall survival of patients who had a major resection was significantly poorer than those who had minor resections (p = 0.028), although the clinical characteristics were comparable between the two groups.
conclusionAlthough the extent of hepatectomy was not an independent prognosticator, minor resections for multiple colorectal metastases may offer a long-term survival advantage compared to a major resection.
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