The role of DNA hypermethylation and demethylation in cancer and cancer therapy.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed.

1. Mechanistic Insights on Metformin and Arginine Implementation as Repurposed Drugs in Glioblastoma Treatment.International journal of molecular sciences · 2024
   Article
2. Predicting drug sensitivity of cancer cells based on DNA methylation levels.PloS one · 2021
   Article
3. Promoter hypermethylation of early B cell factor 1 (EBF1) is associated with cholangiocarcinoma progression.Journal of Cancer · 2021
   Article
4. Aberrantly DNA Methylated-Differentially Expressed Genes in Pancreatic Cancer Through an Integrated Bioinformatics Approach.Frontiers in genetics · 2021
   Article
5. Effect of 5-aza-2'-deoxycytidine on Estrogen Receptor Alpha/Beta and DNA Methyltransferase 1 Genes Expression, Apoptosis Induction, and Cell Growth Prevention of the Colon Cancer HT 29 Cell Line.International journal of preventive medicine · 2020
   Article
6. Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor-An Opportunity for Cancer Treatment.Cells · 2019
   Article
7. Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition.Particle and fibre toxicology · 2018
   Article
8. Genome-wide DNA methylomes from discrete developmental stages reveal the predominance of non-CpG methylation in Tribolium castaneum.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017
   Article
9. Paradoxical roles of dual oxidases in cancer biology.Free radical biology & medicine · 2017
   Review
10. Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates.Scientific reports · 2017
    Article
11. DNA methylation of heparanase promoter influences its expression and associated with the progression of human breast cancer.PloS one · 2014
    Article
12. Overexpression of Testes-Specific Protease 50 (TSP50) Predicts Poor Prognosis in Patients with Gastric Cancer.Gastroenterology research and practice · 2014
    Article
13. Promoter hypomethylation of EpCAM-regulated bone morphogenetic protein gene family in recurrent endometrial cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2013
    Article
14. Next-generation sequencing: from understanding biology to personalized medicine.Biology · 2013
    Article
15. Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway.Scientific reports · 2012
    Article
16. Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome.BMC genomics · 2011
    Article
17. Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes.Epigenetics · 2011
    Article
18. S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer.International journal of biological sciences · 2010
    Article
19. Epigenetic therapeutics in autoimmune disease.Clinical reviews in allergy & immunology · 2010
    Review
20. DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine.Carcinogenesis · 2010
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.