Evidence map›Paper›PMID 18453811›Full record

ArticleJournal of the cardiometabolic syndrome2008

The human immunodeficiency virus and the cardiometabolic syndrome in the developing world: an African perspective.

Eugene Mutimura, Nigel J Crowther, Aimee Stewart, W Todd Cade

Abstract read
In one paragraph

Article in Journal of the cardiometabolic syndrome, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The Influence of Social Support on Smoking Cessation Treatment Adherence Among HIV+ Smokers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2016
    Article
  12. Article
  13. Metabolic syndrome and associated factors among outpatients of Jimma University Teaching Hospital.Diabetes, metabolic syndrome and obesity : targets and therapy · 2016
    Article
  14. Prevalence of Metabolic Syndrome among Working Adults in Ethiopia.International journal of hypertension · 2011
    Article
  15. Article
  16. Article
  17. Cigarette smoking and HIV: more evidence for action.AIDS education and prevention : official publication of the International Society for AIDS Education · 2009
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eugene MutimuraFaculty of Allied Health Sciences and Programs in HIV/AIDS Clinical Research and Community Interventions, Kigali Health Institute, Kigali, Rwanda. eumuran@yahoo.co.uk
Nigel J Crowther
Aimee Stewart
W Todd Cade

Funding

Exercise /TZD Effects on Myocardial Substrate MetabolismK01DK074343 · NIDDK · WASHINGTON UNIVERSITY · PI CADE, WILLIAM TODD · 2006 to 2010
$503k
Designing Research Training for Rwandans in Emerging HIV & Drug Therapy D71TW009618 · FIC · RASD RWANDA · PI MUTIMURA, EUGENE · 2013 to 2014
$60k
FIC NIH HHS D71 TW009618NIDDK NIH HHS K01 DK074343PHS HHS KDK074343A
6 · The paper itself

Abstract

The advent of highly active antiretroviral therapy (HAART) has transformed human immunodeficiency virus (HIV)/AIDS into a manageable chronic disorder. Clinical care, however, needs to address the metabolic, anthropometric, and cardiovascular changes associated with HIV infection and HAART. Studies in developing countries suggest an increasing incidence of HIV-associated cardiometabolic syndrome (CMS), especially in urban settings. Predictions indicate that the greatest increase in the prevalence of diabetes will occur in Africa over the next 2 decades due to lifestyle changes. This, coupled with increased access to HAART, may exponentially increase the prevalence of CMS in developing countries, where HIV infection is prevalent. Appropriate evaluation and intervention programs need to be implemented in the developing world, especially sub-Saharan Africa, to curtail HIV-related CMS. This should include routine cardiovascular risk assessments, management of HIV infection with more "metabolically friendly" HAART, and encouragement of lifestyle modifications, particularly smoking cessation, weight management, regular exercise, and adherence to a healthy diet.

Indexed as

Acquired Immunodeficiency SyndromeAfrica South of the SaharaAntiretroviral Therapy, Highly ActiveCardiovascular DiseasesDeveloping CountriesDiabetes MellitusDietHIVHIV InfectionsHumansLife StyleMetabolic SyndromeNutritional StatusPrevalenceRwandaSyndrome

Identifiers

PMID18453811
PMCPMC4493161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.