ReviewInfectious disease clinics of North America2008
Biology of infection with Borrelia burgdorferi.
Review in Infectious disease clinics of North America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 1 synthesis or guideline pooled it, 245 citations in OpenAlex.
- Global prevalence and species diversity of tick-borne pathogens in buffaloes worldwide: a systematic review and meta-analysis.Parasites & vectors · 2023Pooled it
- The Role of Companion Animals as 'Sentinels' From the One Health Perspective.Veterinary medicine and science · 2026Review
- Prevalence and Risk Factors ofPathogens (Basel, Switzerland) · 2026Article
- Cattle Zoonotic and Non-Zoonotic Tick-Borne Pathogens in Europe-A Retrospective Analysis of the Past 15 Years.Animals : an open access journal from MDPI · 2025Review
- LTT-Validity in diagnosis and therapeutical decision making of neuroborreliosis: a prospective dual-centre study.Infection · 2025Article
- Current Progress in the Development of mRNA Vaccines Against Bacterial Infections.International journal of molecular sciences · 2024Review
- Borrelia PeptideAtlas: A proteome resource of common Borrelia burgdorferi isolates for Lyme research.Scientific data · 2024Article
- Development, Optimization, and Validation of a Quantitative PCR Assay forPathogens (Basel, Switzerland) · 2024Article
- Bioreceptor modified electrochemical biosensors for the detection of life threating pathogenic bacteria: a review.RSC advances · 2024Review
- Not bitten by Ixodes ticks or bitten without symptoms, why still to worry?Central European journal of public health · 2024Article
- Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024Review
- Lyme Disease Models of Tick-Mouse Dynamics with Seasonal Variation in Births, Deaths, and Tick Feeding.Bulletin of mathematical biology · 2024Article
- Pathogenicity and virulence ofVirulence · 2023Review
- Concurrent Infection of the Human Brain with MultipleInternational journal of molecular sciences · 2023Article
- Tick-to-host transmission differs betweenMicrobiology spectrum · 2023Article
- Antigen-Specific CD4 T Cell and B Cell Responses to Borrelia burgdorferi.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
- Static electricity passively attracts ticks onto hosts.Current biology : CB · 2023Article
- Analysis of macerated ticks using Boolean logic gating colorimetric isothermal nucleic acid assays for Lyme Borrelia and Ixodes scapularis ticks.Scientific reports · 2023Article
- Article
- The AxBioTick Study:Microorganisms · 2023Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The spirochete Borrelia burgdorferi is a tick-borne obligate parasite whose normal reservoir is a variety of small mammals. Although infection of these natural hosts does not lead to disease, infection of humans can result in Lyme disease as a consequence of the human immunopathologic response to B burgdorferi. Consistent with the pathogenesis of Lyme disease, bacterial products that allow B burgdorferi to replicate and survive seem to be primarily what is required for the bacterium to cause disease in a susceptible host. This article describes the basic biology of B burgdorferi and reviews some of the bacterial components required for infection of and survival in the mammalian and tick hosts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.