ArticleThe Plant cell2008
Activated expression of an Arabidopsis HD-START protein confers drought tolerance with improved root system and reduced stomatal density.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 2 of them syntheses that pooled it.
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Who cites it
150 citing papers in PubMed, 2 syntheses or guidelines pooled it, 372 citations in OpenAlex.
- Plant responses to high temperature and drought: A bibliometrics analysis.Frontiers in plant science · 2022Pooled it
- A balancing act: how plants integrate nitrogen and water signals.Journal of experimental botany · 2020Pooled it
- CaSNF1 interacts with and phosphorylates CaHD-ZIP to enhance cold tolerance in pepper.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genome-Wide Characterization of the Apple HD-Zip IV Gene Family and Functional Validation of MdHDZIV3 Under PEG-Induced Osmotic Stress.Plants (Basel, Switzerland) · 2026Article
- Stu-miR393-5p-StTIR1A-StPLC2 module regulates the development of adventitious and lateral roots of potato.Plant cell reports · 2026Article
- Evolutionary Diversification and Adaptive Evolution Analysis of the Plant HD-Zip IV Subfamily.Genes · 2025Article
- Genome-wide identification and expression analysis of HD-ZIP gene family in sunflower (Helianthus annuus L.) under water deficit stress.Scientific reports · 2025Article
- Investigating how reproductive traits in rice respond to abiotic stress.Journal of experimental botany · 2025Review
- Stomatal development in the changing climate.Development (Cambridge, England) · 2024Review
- KIN10-mediated HB16 protein phosphorylation and self-association improve cassava disease resistance by transcriptional activation of lignin biosynthesis genes.Plant biotechnology journal · 2024Article
- Article
- The F-Box Protein TaFBA1 Positively Regulates Drought Resistance and Yield Traits in Wheat.Plants (Basel, Switzerland) · 2024Article
- HD-ZIP IV Gene ROC1 Regulates Leaf Rolling and Drought Response Through Formation of Heterodimers with ROC5 and ROC8 in Rice.Rice (New York, N.Y.) · 2024Article
- Trait variation and performance across varying levels of drought stress in cultivated sunflower (AoB PLANTS · 2024Article
- Genome-wide characterisation of HD-Zip transcription factors and functional analysis of PbHB24 during stone cell formation in Chinese white pear (Pyrus bretschneideri).BMC plant biology · 2024Article
- Article
- Overexpression ofFrontiers in plant science · 2024Article
- Genome-wide identification and expression analysis ofFrontiers in genetics · 2024Article
- Distinct guard cell-specific remodeling of chromatin accessibility during abscisic acid- and COProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Natural polymorphisms in ZmIRX15A affect water-use efficiency by modulating stomatal density in maize.Plant biotechnology journal · 2023Article
90 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Drought is one of the most important environmental constraints limiting plant growth and agricultural productivity. To understand the underlying mechanism of drought tolerance and to identify genes for improving this important trait, we conducted a gain-of-function genetic screen for improved drought tolerance in Arabidopsis thaliana. One mutant with improved drought tolerance was isolated and designated as enhanced drought tolerance1. The mutant has a more extensive root system than the wild type, with deeper roots and more lateral roots, and shows a reduced leaf stomatal density. The mutant had higher levels of abscisic acid and Pro than the wild type and demonstrated an increased resistance to oxidative stress and high levels of superoxide dismutase. Molecular genetic analysis and recapitulation experiments showed that the enhanced drought tolerance is caused by the activated expression of a T-DNA tagged gene that encodes a putative homeodomain-START transcription factor. Moreover, overexpressing the cDNA of the transcription factor in transgenic tobacco also conferred drought tolerance associated with improved root architecture and reduced leaf stomatal density. Therefore, we have revealed functions of the homeodomain-START factor that were gained upon altering its expression pattern by activation tagging and provide a key regulator that may be used to improve drought tolerance in plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.