ArticlePlant physiology2008
The "old" Euonymus europaeus agglutinin represents a novel family of ubiquitous plant proteins.
Article in Plant physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 43 citations in OpenAlex.
- Rice Lectin Protein r40c1 Interacts With Magnaporthe oryzae Sho1 Protein to Regulate Leaf Blast Resistance.Plant, cell & environment · 2026Article
- Mutation of a gene with PWWP domain confers salt tolerance in rice.Plant molecular biology · 2025Article
- 130 years of Plant Lectin Research.Glycoconjugate journal · 2020Review
- Evolutionary relationships and expression analysis of EUL domain proteins in rice (Oryza sativa).Rice (New York, N.Y.) · 2017Article
- Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.British journal of cancer · 2016Article
- Insights into animal and plant lectins with antimicrobial activities.Molecules (Basel, Switzerland) · 2015Review
- Detection of distinct glycosylation patterns on human γ-glutamyl transpeptidase 1 using antibody-lectin sandwich array (ALSA) technology.BMC biotechnology · 2014Article
- Lectin domains at the frontiers of plant defense.Frontiers in plant science · 2014Review
- Promiscuity of the euonymus carbohydrate-binding domain.Biomolecules · 2012Article
- Expression analysis of a type S2 EUL-related lectin from rice in Pichia pastoris.Glycoconjugate journal · 2012Article
- A novel lectin from Agrocybe aegerita shows high binding selectivity for terminal N-acetylglucosamine.The Biochemical journal · 2012Article
- Lectin activity of the nucleocytoplasmic EUL protein from Arabidopsis thaliana.Biochemical and biophysical research communications · 2011Article
- Evolutionary history and stress regulation of the lectin superfamily in higher plants.BMC evolutionary biology · 2010Article
- Proteins with an Euonymus lectin-like domain are ubiquitous in Embryophyta.BMC plant biology · 2009Article
- PLecDom: a program for identification and analysis of plant lectin domains.Nucleic acids research · 2009Article
- Plant lectins: the ties that bind in root symbiosis and plant defense.Molecular genetics and genomics : MGG · 2009Review
- Combined proteomic and cytological analysis of Ca2+-calmodulin regulation in Picea meyeri pollen tube growth.Plant physiology · 2009Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
Molecular cloning of the "old" but still unclassified Euonymus europaeus agglutinin (EEA) demonstrated that the lectin is a homodimeric protein composed of 152 residue subunits. Analysis of the deduced sequence indicated that EEA is synthesized without a signal peptide and undergoes no posttranslational processing apart from the removal of a six-residue N-terminal peptide. Glycan array screening confirmed the previously reported high reactivity of EEA toward blood group B oligosaccharides but also revealed binding to high mannose N-glycans, providing firm evidence for the occurrence of a plant carbohydrate-binding domain that can interact with structurally different glycans. Basic Local Alignment Search Tool searches indicated that EEA shares no detectable sequence similarity with any other lectin but is closely related evolutionarily to a domain that was first identified in some abscisic acid- and salt stress-responsive rice (Oryza sativa) proteins, and, according to the available sequence data, might be ubiquitous in Spermatophyta. Hence, EEA can be considered the prototype of a novel family of presumably cytoplasmic/nuclear proteins that are apparently ubiquitous in plants. Taking into account that some of these proteins are definitely stress related, the present identification of the EEA lectin domain might be a first step in the recognition of the involvement and importance of protein-glycoconjugate interactions in some essential cellular processes in Embryophyta.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.