Evidence map›Paper›PMID 18450663›Full record

ArticleThe British journal of psychiatry : the journal of mental science2008

Disability and treatment of specific mental and physical disorders across the world.

Johan Ormel, Maria Petukhova, Somnath Chatterji, Sergio Aguilar-Gaxiola, Jordi Alonso, Matthias C Angermeyer, Evelyn J Bromet, Huibert Burger, Koen Demyttenaere, Giovanni de Girolamo and 14 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06783842 (Perioperative Depression, an Observational Cohort Study), which is not on this map. Cited by 141 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 2 pooled it
27.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06783842 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Perioperative Depression, an Observational Cohort Study

Typeobservational_patient_registrySponsorKarolinska InstitutetRan2025 to 2026Enrolled700,000ConditionsSurgery With General Anesthesia, Depression - Major Depressive Disorder
3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 2 syntheses or guidelines pooled it, 389 citations in OpenAlex.

  1. Pooled it
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  12. Anxiety and depression in emerging adults: The STAND program as a model of scalable screening and intervention.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  13. Article
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  18. Major depressive disorder.Nature reviews. Disease primers · 2023
    Review
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  20. Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 19 institutions in 14 countries.

Johan OrmelDepartment of Psychiatry, University Medical Center Groningen, and Graduate School of Behavioural and Cognitive Neurosciences & Graduate School for Experimental Psychopathology, University of Groningen, The Netherlands.
Maria Petukhova
Somnath Chatterji
Sergio Aguilar-Gaxiola
Jordi Alonso
Matthias C Angermeyer
Evelyn J Bromet
Huibert Burger
Koen Demyttenaere
Giovanni de Girolamo
Josep Maria Haro
Irving Hwang
Elie Karam
Norito Kawakami
Jean Pierre Lépine
María Elena Medina-Mora
José Posada-Villa
Nancy Sampson
Kate Scott
T Bedirhan Ustün
Michael Von Korff
David R Williams
Mingyuan Zhang
Ronald C Kessler
Harvard University · USUniversity Medical Center Groningen · NLWorld Health Organization · CHAzienda USL di Bologna · ITGroup Health Cooperative · USHôpital Fernand-Widal · FRHospital Sant Joan de Déu Barcelona · ESInstitute for Development, Research, Advocacy and Applied Care · LBLeipzig University · DEMexican Social Security Institute · MXMunicipal Institute for Medical Research · ESShanghai Mental Health Center · CNStony Brook University · USThe University of Tokyo · JPUniversidad Colegio Mayor de Cundinamarca · COUniversitair Ziekenhuis Leuven · BEUniversity of California, Davis · USUniversity of Michigan–Ann Arbor · USUniversity of Otago · NZ

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Trauma, Stress, and Mental Health in South AfricaR01MH059575 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WILLIAMS, DAVID R · 1998 to 2007
$2.5M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
COMORBID MENTAL DISORDERS IN PERIODS OF SOCIAL DISRUPTIOR01MH061905 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI BROMET, EVELYN J · 2000 to 2004
$1.7M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
Drug Dependence Epidemiology and EnviromicsK05DA015799 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2015
$1.4M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
World Mental Health Consortium Annual Meetings 2008-2012U13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2008 to 2012
$647k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R01 TW 006481FIC NIH HHS R03 TW 0006481FIC NIH HHS R03 TW006481NIDA NIH HHS K05 DA015799NIDA NIH HHS R01 DA 016558NIDA NIH HHS R01 DA016558NIMH NIH HHS HHSN271200700030CNIMH NIH HHS R01 MH 059575NIMH NIH HHS R01 MH059575NIMH NIH HHS R01 MH061905NIMH NIH HHS R01 MH069864NIMH NIH HHS R01 MH 070884NIMH NIH HHS R01 MH070884NIMH NIH HHS R01 MH 61905NIMH NIH HHS R13 MH 066849NIMH NIH HHS R13 MH066849NIMH NIH HHS U01 MH060220NIMH NIH HHS U01 MH 60220NIMH NIH HHS U13 MH066849PHS HHS HHSN 271200700030CPHS HHS R01 069864
6 · The paper itself

Abstract

backgroundAdvocates of expanded mental health treatment assert that mental disorders are as disabling as physical disorders, but little evidence supports this assertion.

aimsTo establish the disability and treatment of specific mental and physical disorders in high-income and low- and middle-income countries.

methodCommunity epidemiological surveys were administered in 15 countries through the World Health Organization World Mental Health (WMH) Survey Initiative.

resultsRespondents in both high-income and low- and middle-income countries attributed higher disability to mental disorders than to the commonly occurring physical disorders included in the surveys. This pattern held for all disorders and also for treated disorders. Disaggregation showed that the higher disability of mental than physical disorders was limited to disability in social and personal role functioning, whereas disability in productive role functioning was generally comparable for mental and physical disorders.

conclusionsDespite often higher disability, mental disorders are under-treated compared with physical disorders in both high-income and in low- and middle-income countries.

Indexed as

Chronic DiseaseGlobal HealthHealth StatusMental DisordersActivities of Daily LivingCost of IllnessCross-Cultural ComparisonEpidemiologic MethodsHealth Services AccessibilityHumans

Identifiers

PMID18450663
PMCPMC2681238
OpenAlexW2171668194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.