Evidence map›Paper›PMID 18449525›Full record

ReviewDiabetologia2008

The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted.

Z T Bloomgarden, S E Inzucchi, E Karnieli, D Le Roith

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Diabetologia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 50 citations in OpenAlex.

  1. GLYCATED ALBUMIN AT 4 WEEKS CORRELATES WITH A1C LEVELS AT 12 WEEKS AND REFLECTS SHORT-TERM GLUCOSE FLUCTUATIONS.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2015
    Trial
  2. Article
  3. Results of a Study Comparing Glycated Albumin to Other Glycemic Indices.The Journal of clinical endocrinology and metabolism · 2020
    Article
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  6. Prediabetes diagnosis and treatment: A review.World journal of diabetes · 2015
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Z T BloomgardenMount Sinai School of Medicine, New York, NY 10028, USA. zbloomgard@aol.com
S E Inzucchi
E Karnieli
D Le Roith
Icahn School of Medicine at Mount Sinai · USRambam Health Care Campus · ILYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proposed use of a more precise standard for glycated (A(1c)) and non-glycated haemoglobin would lead to an A(1c) value, when expressed as a percentage, that is lower than that currently in use. One approach advocated to address the potential confusion that would ensue is to replace 'HbA(1c)' with a new term, 'A(1c)-derived average glucose.' We review evidence from several sources suggesting that A(1c) is, in fact, inherently imprecise as a measure of average glucose, so that the proposed terminology should not be adopted.

Indexed as

Blood GlucoseGlycated HemoglobinTerminology as TopicChemistry, ClinicalDiabetes MellitusHumansReproducibility of ResultsBlood GlucoseGlycated Hemoglobin

Identifiers

PMID18449525
OpenAlexW2006188109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.