Evidence map›Paper›PMID 18448695›Full record

ArticleJournal of clinical microbiology2008

Occult hepatitis C virus infection revisited with ultrasensitive real-time PCR assay.

Philippe Halfon, Marc Bourlière, Denis Ouzan, Damien Sène, David Saadoun, Hacène Khiri, Guillaume Pénaranda, Agnes Martineau, Valérie Oulès, Patrice Cacoub

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Occult HCV Infection: The Current State of Knowledge.Iranian Red Crescent medical journal · 2015
    Review
  3. A New Twist to a Chronic HCV Infection: Occult Hepatitis C.Gastroenterology research and practice · 2015
    Review
  4. Article
  5. Review
  6. Occult hepatitis C virus infection and its relevance in clinical practice.Journal of clinical and experimental hepatology · 2011
    Article
  7. Does occult hepatitis C virus infection exist?Journal of clinical microbiology · 2008
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Philippe HalfonLaboratoire Alphabio, 23 rue de Friedland, Hôpital Ambroise Paré, 13006 Marseille, France. philippe.halfon@alphabio.fr
Marc Bourlière
Denis Ouzan
Damien Sène
David Saadoun
Hacène Khiri
Guillaume Pénaranda
Agnes Martineau
Valérie Oulès
Patrice Cacoub

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occult hepatitis C infection is regarded as a new entity that should be considered when diagnosing patients with a liver disease of unknown origin. Using an ultrasensitive real-time PCR assay, we demonstrated that occult hepatitis C virus (HCV) infection cannot be found in peripheral blood mononuclear cells of patients with cryptogenic liver diseases, HCV--associated systemic vasculitis, or connective tissue diseases. The significance of such occult infection must be elucidated.

Indexed as

Virus ReplicationAdultAgedConnective Tissue DiseasesFemaleHepacivirusHepatitis CHumansLeukocytes, MononuclearLiverLiver DiseasesLiver Function TestsMaleMiddle AgedPolymerase Chain ReactionRNA, ViralRNA, Viral

Identifiers

PMID18448695
PMCPMC2446830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.