ReviewSchizophrenia bulletin2008
Neurocognitive allied phenotypes for schizophrenia and bipolar disorder.
Review in Schizophrenia bulletin, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 125 citations in OpenAlex.
- Relational Memory in Psychosis: Learning Trajectories and Associative Inference.Schizophrenia bulletin · 2026Article
- Differences in social adjustment during adulthood between adoptees with high and low risk for schizophrenia spectrum disorders - the Finnish adoptive family study of schizophrenia.European archives of psychiatry and clinical neuroscience · 2025Article
- Associations between Sjogren syndrome and psychiatric disorders in European populations: a 2-sample bidirectional Mendelian randomization study.Frontiers in psychiatry · 2024Article
- Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study.Psychological medicine · 2023Article
- Early cognitive comorbidities before disease onset: A common symptom towards prevention of related brain diseases?Heliyon · 2022Review
- Deficits in generalized cognitive ability, visual sensorimotor function, and inhibitory control represent discrete domains of neurobehavioral deficit in psychotic disorders.Schizophrenia research · 2021Article
- Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Increased and Decreased Superficial White Matter Structural Connectivity in Schizophrenia and Bipolar Disorder.Schizophrenia bulletin · 2019Article
- The role of childhood trauma in cognitive performance in schizophrenia and bipolar disorder - A systematic review.Schizophrenia research. Cognition · 2019Review
- Cognitive burden of anticholinergic medications in psychotic disorders.Schizophrenia research · 2017Article
- Unitary construct of generalized cognitive ability underlying BACS performance across psychotic disorders and in their first-degree relatives.Schizophrenia research · 2016Article
- Role of presynaptic phosphoprotein synapsin II in schizophrenia.World journal of psychiatry · 2015Article
- Shared and distinct neurocognitive endophenotypes of schizophrenia and psychotic bipolar disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2015Article
- Schizotypy--do not worry, it is not all worrisome.Schizophrenia bulletin · 2015Review
- Hippocampal volume is reduced in schizophrenia and schizoaffective disorder but not in psychotic bipolar I disorder demonstrated by both manual tracing and automated parcellation (FreeSurfer).Schizophrenia bulletin · 2015Article
- Large-Scale Fusion of Gray Matter and Resting-State Functional MRI Reveals Common and Distinct Biological Markers across the Psychosis Spectrum in the B-SNIP Cohort.Frontiers in psychiatry · 2015Article
- A genome-wide supported psychiatric risk variant in NCAN influences brain function and cognitive performance in healthy subjects.Human brain mapping · 2015Article
- Emotion recognition deficits in schizophrenia-spectrum disorders and psychotic bipolar disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study.Schizophrenia research · 2014Article
- From neural signatures of emotional modulation to social cognition: individual differences in healthy volunteers and psychiatric participants.Social cognitive and affective neuroscience · 2014Article
- A genome-wide supported variant in CACNA1C influences hippocampal activation during episodic memory encoding and retrieval.European archives of psychiatry and clinical neuroscience · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Psychiatric disorders are genetically complex and represent the end product of multiple biological and social factors. Links between genes and disorder-related abnormalities can be effectively captured via assessment of phenotypes that are both associated with genetic effects and potentially contributory to behavioral abnormalities. Identifying intermediate or allied phenotypes as a strategy for clarifying genetic contributions to disorders has been successful in other areas of medicine and is a promising strategy for identifying susceptibility genes in complex psychiatric disorders. There is growing evidence that schizophrenia and bipolar disorder, rather than being wholly distinct disorders, share genetic risk at several loci. Further, there is growing evidence of similarity in the pattern of cognitive and neurobiological deficits in these groups, which may be the result of the effects of these common genetic factors. This review was undertaken to identify patterns of performance on neurocognitive and affective tasks across probands with schizophrenia and bipolar disorder as well as unaffected family members, which warrant further investigation as potential intermediate trait markers. Available evidence indicates that measures of attention regulation, working memory, episodic memory, and emotion processing offer potential for identifying shared and illness-specific allied neurocognitive phenotypes for schizophrenia and bipolar disorder. However, very few studies have evaluated neurocognitive dimensions in bipolar probands or their unaffected relatives, and much work in this area is needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.