ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2008
Relation between myocardial edema and myocardial mass during the acute and convalescent phase of myocarditis--a CMR study.
Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 87 citations in OpenAlex.
- Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: primary results of the ARCHER study.ESC heart failure · 2026Trial
- Retrospective Evaluation of Anesthetic-Analgesic Protocols in Cats with and Without Transient Myocardial Thickening Following Gonadectomy.Animals : an open access journal from MDPI · 2026Article
- Arterial Thromboembolism in a Seven-Month-Old Cat with Acute Myocardial Injury.Animals : an open access journal from MDPI · 2026Article
- TIGAR deficiency enhances cardiac resilience through epigenetic programming of Parkin expression.JCI insight · 2026Article
- Haemodynamic implications of cardiovascular magnetic resonance pulmonary capillary wedge pressure in acute myocardial infarction.European heart journal. Imaging methods and practice · 2025Article
- Successful Management of Recurrent Pyothorax in a Cat: Clinical Findings with Medical and Surgical Approaches.Animals : an open access journal from MDPI · 2025Article
- Transient restrictive cardiomyopathy in cats: first reported case series.Frontiers in veterinary science · 2025Article
- Mechanisms of Myocardial Edema Development in CVD Pathophysiology.Biomedicines · 2024Review
- Interaction Between Blood Vasculatures and Lymphatic Vasculatures During Inflammation.Journal of inflammation research · 2023Review
- Peripartum Cardiomyopathy: Diagnostic and Prognostic Value of Cardiac Magnetic Resonance in the Acute Stage.Diagnostics (Basel, Switzerland) · 2022Article
- Myocardial Edema Revisited in a New Paradigm of Cardiac Electrical Microcurrent Application in Heart Failure.Bioelectricity · 2021Article
- An unusual case of apical myocarditis: a case report.European heart journal. Case reports · 2020Article
- Relapse of acute myocarditis associated withClinical case reports · 2020Article
- Multimodality Imaging in Evaluation of Cardiovascular Complications in Patients With COVID-19: JACC Scientific Expert Panel.Journal of the American College of Cardiology · 2020Review
- Cardiac structure and function in patients with schizophrenia taking antipsychotic drugs: an MRI study.Translational psychiatry · 2019Article
- Value of cardiac magnetic resonance imaging in systemic sclerosis.Reumatologia · 2018Article
- Transient Myocardial Thickening in Cats Associated with Heart Failure.Journal of veterinary internal medicine · 2018Article
- Assessment of edema using STIR+ via 3D cardiovascular magnetic resonance imaging in patients with suspected myocarditis.Magma (New York, N.Y.) · 2017Article
- [Myocarditis in the differential diagnosis of cardiomyopathies. Endomyocardial biopsy or MRI?].Herz · 2015Review
- Magnetic resonance imaging and multi-detector computed tomography assessment of extracellular compartment in ischemic and non-ischemic myocardial pathologies.World journal of cardiology · 2014Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial edema is a substantial feature of the inflammatory response in human myocarditis. The relation between myocardial edema and myocardial mass in the course of healing myocarditis has not been systematically investigated. We hypothesised that the resolution of myocardial edema as visualised by T2-weighted cardiovascular magnetic resonance (CMR) is associated with a decrease of myocardial mass in steady state free precession (SSFP)-cine imaging.
methods21 patients with acute myocarditis underwent CMR shortly after onset of symptoms and 1 year later. For visualization of edema, a T2-weighted breath-hold black-blood triple-inversion fast spin echo technique was applied and the ratio of signal intensity of myocardium/skeletal muscle was assessed. Left ventricular (LV) mass, volumes and function were quantified from biplane cine steady state free precession images. 11 healthy volunteers served as a control group for interstudy reproducibility of LV mass.
resultsIn patients with myocarditis, a significant decrease in LV mass was observed during follow-up compared to the acute phase (156.7 +/- 30.6 g vs. 140.3 +/- 28.3 g, p < 0.0001). The reduction of LV mass paralleled the normalization of initially increased myocardial signal intensity on T2-weighted images (2.4 +/- 0.4 vs. 1.68 +/- 0.3, p < 0.0001). In controls, the interstudy difference of LV mass was lower than in patients (5.1 +/- 2.9 g vs. 16.3 +/- 14.2 g, p = 0.02) resulting in a lower coefficient of variability (2.1 vs 8.9%, p = 0.04).
conclusionReversible abnormalities in T2-weighted CMR are paralleled by a transient increase in left ventricular mass during the course of myocarditis. Myocardial edema may be a common pathway explaining these findings.
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