ArticleIntensive care medicine2008
Primary and secondary intra-abdominal hypertension--different impact on ICU outcome.
Article in Intensive care medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective, Interventional Multicentre Study on the Effect of Deepening of Sedation on Intra-abdominal Pressure
Closed Versus Open Abdomen in the Surgical Treatment of Severe Secondary Peritonitis: a Randomized Controlled Clinical Trial
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Risk factors for intra-abdominal hypertension and abdominal compartment syndrome among adult intensive care unit patients: a systematic review and meta-analysis.Critical care (London, England) · 2013Pooled it
- The effect of diabetes on mortality in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2011Pooled it
- Increased intra-abdominal pressure linked to worse long-term prognosis among patients with orthotopic liver transplantation: a retrospective, observational study.BMC gastroenterology · 2025Observational
- International cross-sectional survey on current and updated definitions of intra-abdominal hypertension and abdominal compartment syndrome.World journal of emergency surgery : WJES · 2024Article
- Expert consensus on blood pressure management in critically ill patients.Journal of intensive medicine · 2023Article
- Fluid Management, Intra-Abdominal Hypertension and the Abdominal Compartment Syndrome: A Narrative Review.Life (Basel, Switzerland) · 2022Review
- Impact of intra-abdominal pressure on early kidney transplant outcomes.Scientific reports · 2022Article
- Role of intra-abdominal pressure in the outcomes of perforation peritonitis: A prospective observational study.Turkish journal of surgery · 2021Article
- Intra-abdominal hypertension and abdominal compartment syndrome in patients admitted to the ICU.Annals of intensive care · 2020Article
- A Case of Lethal Abdominal Compartment Syndrome due to Rapidly Expanding Ovarian Small Cell Carcinoma Pulmonary Type.Cureus · 2020Article
- Incidence, Risk Factors, and Outcomes of Intra-Abdominal Hypertension in Critically Ill Patients-A Prospective Multicenter Study (IROI Study).Critical care medicine · 2019Observational
- Decompressive laparotomy for abdominal compartment syndrome.The British journal of surgery · 2016Article
- Mild to moderate intra-abdominal hypertension: Does it matter?World journal of critical care medicine · 2016Review
- Article
- Intra-abdominal hypertension in the ICU - a prospective epidemiological study.Clujul medical (1957) · 2015Article
- Moderate intra-abdominal hypertension leads to anaerobic metabolism in the rectus abdominis muscle tissue of critically ill patients: a prospective observational study.BioMed research international · 2014Observational
- Standardized application of laxatives and physical measures in neurosurgical intensive care patients improves defecation pattern but is not associated with lower intracranial pressure.Critical care research and practice · 2014Article
- Compression of the inferior vena cava in bowel obstruction.BioMed research international · 2013Article
- Matching positive end-expiratory pressure to intra-abdominal pressure improves oxygenation in a porcine sick lung model of intra-abdominal hypertension.Critical care (London, England) · 2012Article
- Incidence and prognosis of intra-abdominal hypertension in critically ill medical patients: a prospective epidemiological study.Annals of intensive care · 2012Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the differences in incidence, time course and outcome of primary versus secondary intra-abdominal hypertension (IAH), and to evaluate IAH as an independent risk factor of mortality in a presumable risk population of critically ill patients.
designProspective observational study.
settingGeneral intensive care unit of a university hospital. PATIENTS: A total of 257 mechanically ventilated patients at presumable risk for the development of IAH were studied during their ICU stay and followed up for 90-day survival.
interventionsRepeated measurements of intra-abdominal pressure (IAP). MEASUREMENTS AND
resultsIAP was measured intermittently, via bladder. IAH (sustained or repeated IAP > or = 12 mmHg) developed in 95 patients (37.0%). Primary IAH was observed in 60 and secondary IAH in 35 patients. Patients with secondary IAH demonstrated a significant increase of mean IAP during the first three days (mean DeltaIAP was 2.2 +/- 4.7 mmHg), whilst IAP decreased (mean DeltaIAP -1.1 +/- 3.7 mmHg) in the patients with primary IAH. The patients with IAH had a significantly higher ICU- (37.9 vs. 19.1%; P = 0.001), 28-day (48.4 vs. 27.8%, P = 0.001), and 90-day mortality (53.7 vs. 35.8%, P = 0.004) compared to the patients without the syndrome. Patients with secondary IAH had a significantly higher ICU mortality than patients with primary IAH (P = 0.032). Development of IAH was identified as an independent risk factor for death (OR 2.52; 95% CI 1.23-5.14).
conclusionsSecondary IAH is less frequent, has a different time course and worse outcome than primary IAH. Development of IAH during ICU period is an independent risk factor for death.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.