ArticlePloS one2008
The mych gene is required for neural crest survival during zebrafish development.
Article in PloS one, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Phenotypically anchored transcriptomics across diverse agrichemicals reveals conserved pathways and unique gene expression signatures in zebrafish.Frontiers in toxicology · 2025Article
- Mycb and Mych stimulate Müller glial cell reprogramming and proliferation in the uninjured and injured zebrafish retina.Development (Cambridge, England) · 2024Article
- Genomic screening of fish-specific genes in gnathostomes and their functions in fin development.Development, growth & differentiation · 2024Article
- An atlas of neural crest lineages along the posterior developing zebrafish at single-cell resolution.eLife · 2021Article
- On the road again: Establishment and maintenance of stemness in the neural crest from embryo to adulthood.Stem cells (Dayton, Ohio) · 2021Review
- MYC in Brain Development and Cancer.International journal of molecular sciences · 2020Review
- Neural crest development: insights from the zebrafish.Developmental dynamics : an official publication of the American Association of Anatomists · 2020Review
- Transcriptome profiling analysis of sex-based differentially expressed mRNAs and lncRNAs in the brains of mature zebrafish (Danio rerio).BMC genomics · 2019Article
- cMyc Regulates the Size of the Premigratory Neural Crest Stem Cell Pool.Cell reports · 2016Article
- Orthotopic models of pediatric brain tumors in zebrafish.Oncogene · 2015Article
- Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation.PloS one · 2014Article
- Zebrafish cancer: the state of the art and the path forward.Nature reviews. Cancer · 2013Review
- Stemness and inducing differentiation of small cell lung cancer NCI-H446 cells.Cell death & disease · 2013Article
- Constitutive gray hair in mice induced by melanocyte-specific deletion of c-Myc.Pigment cell & melanoma research · 2012Article
- Article
- Large-scale analysis of acute ethanol exposure in zebrafish development: a critical time window and resilience.PloS one · 2011Article
- NF-kappaB and Snail1a coordinate the cell cycle with gastrulation.The Journal of cell biology · 2009Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundAmong Myc family genes, c-Myc is known to have a role in neural crest specification in Xenopus and in craniofacial development in the mouse. There is no information on the function of other Myc genes in neural crest development, or about any developmental role of zebrafish Myc genes. PRINCIPAL
findingsWe isolated the zebrafish mych (myc homologue) gene. Knockdown of mych leads to severe defects in craniofacial development and in certain other tissues including the eye. These phenotypes appear to be caused by cell death in the neural crest and in the eye field in the anterior brain. SIGNIFICANCE: Mych is a novel factor required for neural crest cell survival in zebrafish.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.