ArticlePloS one2008
C. albicans colonization of human mucosal surfaces.
Article in PloS one, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Novel domain-structure-containing chitinases A and B of Bacillus velezensis produced by recombinant Escherichia coli cells: Synergism on chitin degradation and their potential in suppressing Candida albicans cell germination.Journal, genetic engineering & biotechnology · 2024Article
- Scaffold diversity for enhanced activity of glycosylated inhibitors of fungal adhesion.RSC medicinal chemistry · 2020Article
- Recognition ofMicroorganisms · 2020Review
- Antimicrobial and antibiofilm activity of the EeCentrocin 1 derived peptide EC1-17KV via membrane disruption.EBioMedicine · 2020Article
- Oral Candidiasis: A Disease of Opportunity.Journal of fungi (Basel, Switzerland) · 2020Review
- Article
- Epidemiology and Outcomes of Candidemia in a Referral Center in Tehran.Caspian journal of internal medicine · 2019Article
- The Role ofFrontiers in microbiology · 2018Article
- The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.Nature communications · 2017Article
- Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition.Scientific reports · 2017Article
- Candida albicans Pathogenesis: Fitting within the Host-Microbe Damage Response Framework.Infection and immunity · 2016Review
- Human Epithelial Cells Discriminate between Commensal and Pathogenic Interactions with Candida albicans.PloS one · 2016Article
- Distinct roles of Candida albicans-specific genes in host-pathogen interactions.Eukaryotic cell · 2014Article
- Insight into the antiadhesive effect of yeast wall protein 1 of Candida albicans.Eukaryotic cell · 2012Article
- Histopathologic diagnosis of fungal infections in the 21st century.Clinical microbiology reviews · 2011Review
- Article
- Association between multiple sclerosis and Candida species: evidence from a case-control study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2010Article
- Capric acid secreted by S. boulardii inhibits C. albicans filamentous growth, adhesion and biofilm formation.PloS one · 2010Article
- The Candida albicans ESCRT pathway makes Rim101-dependent and -independent contributions to pathogenesis.Eukaryotic cell · 2010Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundCandida albicans is a low level commensal organism in normal human populations with the continuous potential to expand and cause a spectrum of clinical conditions. METHODOLOGY/PRINCIPAL
findingsUsing ex vivo human organ cultures and populations of primary human cells, we have developed several related experimental systems to examine early-stage interactions between C. albicans and mucosal surfaces. Experiments have been conducted both with exogenously added C. albicans and with overtly normal human mucosal surfaces supporting pre-existing infections with natural isolates of Candida. Under different culture conditions, we have demonstrated the formation of C. albicans colonies on human target cells and filament formation, equivalent to tissue invasion. CONCLUSIONS/SIGNIFICANCE: These organ culture systems provide a valuable new resource to examine the molecular and cellular basis for Candida colonization of human mucosal surfaces.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.