ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2008
Effects of corticosteroids on oxidative damage and circulating carotenoids in captive adult kestrels (Falco tinnunculus).
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Pooled it
- A meta-analysis of glucocorticoids as modulators of oxidative stress in vertebrates.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2011Pooled it
- Integrating Molt Migration Into Physiological Assessments of Inter-Population Stress in a Globally Endangered Species.Ecology and evolution · 2026Article
- Biochemical and Genomic Underpinnings of Carotenoid Colour Variation Across a Hybrid Zone Between South Asian Flameback Woodpeckers.Molecular ecology · 2025Article
- Activation of the sympathetic-adrenal-medullary system increases DNA damage during the transition to captivity.Integrative organismal biology (Oxford, England) · 2025Article
- Baseline glucocorticoids alone do not predict reproductive success across years, but in interaction with enzymatic antioxidants.Ecology and evolution · 2024Article
- The price of defence: toxins, visual signals and oxidative state in an aposematic butterfly.Proceedings. Biological sciences · 2023Article
- GR-mediated transcriptional regulation of mJournal of animal science and biotechnology · 2021Article
- The role of Rhodotorula mucilaginosa in selected biological process of wild fish.Fish physiology and biochemistry · 2019Article
- Meta-analysis reveals that reproductive strategies are associated with sexual differences in oxidative balance across vertebrates.Current zoology · 2018Article
- Using pentosidine and hydroxyproline to predict age and sex in an avian species.Ecology and evolution · 2017Article
- Effects of corticosterone on the metabolic activity of cultured chicken chondrocytes.BMC veterinary research · 2015Article
- Interactions between Biliverdin, Oxidative Damage, and Spleen Morphology after Simulated Aggressive Encounters in Veiled Chameleons.PloS one · 2015Article
- Repeated stressors in adulthood increase the rate of biological ageing.Frontiers in zoology · 2015Article
- Energy Expenditure and Metabolic Changes of Free-Flying Migrating Northern Bald Ibis.PloS one · 2015Article
- Carotenoid-based coloration in cichlid fishes.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2014Review
- Frugivory is associated with low measures of plasma oxidative stress and high antioxidant concentration in free-ranging bats.Die Naturwissenschaften · 2014Article
- Synchronizing feather-based measures of corticosterone and carotenoid-dependent signals: what relationships do we expect?Oecologia · 2014Article
- Experimental food restriction reveals individual differences in corticosterone reaction norms with no oxidative costs.PloS one · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Birds control body homeostasis through the secretion of corticosterone. This hormone is the end-product of the hypothalamic-pituitary-adrenal (HPA) axis response to stressors. High levels of corticosterone may be associated with low individual fitness and may affect balance between pro-oxidants and antioxidants. Given these points, chronic stress modulated by hormones could undermine individual fitness by increasing oxidative tissue damage. In this study, we administered corticosteroids by diet (20 mg/kg of diet) to captive adult kestrels (Falco tinnunculus) over a 14-day period to evaluate the effects of a simulated chronic stress modulated by corticosteroids. We found that dietary administration of corticosterone caused a 32% increase of reactive oxygen metabolites, but did not impair total serum antioxidant capacity, serum carotenoids or body mass. Oxidative stress had a 64% increase in treated birds compared to 30% in controls. The two groups did not differ in the total serum antioxidant capacity, which showed a significant decrease over the study period. In contrast, circulating carotenoids and body mass increased in both groups. These results suggest that stress hormones, such as corticosterone, may also act as modulators of oxidative stress in birds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.