ArticleAntimicrobial agents and chemotherapy2008
Synergy of human immunodeficiency virus protease inhibitors with chloroquine against Plasmodium falciparum in vitro and Plasmodium chabaudi in vivo.
Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- HIV-1 protease inhibitors and clinical malaria: a secondary analysis of the AIDS Clinical Trials Group A5208 study.Antimicrobial agents and chemotherapy · 2012Trial
- The risk of QTc-interval prolongation in COVID-19 patients treated with chloroquine.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2020Article
- 4-Aryl Pyrrolidines as Novel Orally Efficacious Antimalarial Agents. Part 2: 2-Aryl-ACS medicinal chemistry letters · 2019Article
- 4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides.Journal of medicinal chemistry · 2019Article
- Malaria and HIV coinfection in sub-Saharan Africa: prevalence, impact, and treatment strategies.Research and reports in tropical medicine · 2018Review
- Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs.Antimicrobial agents and chemotherapy · 2017Article
- Pharmacokinetic interactions between artesunate-mefloquine and ritonavir-boosted lopinavir in healthy Thai adults.Malaria journal · 2015Article
- Presence of Plasmodium falciparum DNA in Plasma Does Not Predict Clinical Malaria in an HIV-1 Infected Population.PloS one · 2015Article
- Chloroquine-containing compounds: a patent review (2010 - 2014).Expert opinion on therapeutic patents · 2015Review
- Identification of endoplasmic reticulum stress-inducing agents by antagonizing autophagy: a new potential strategy for identification of anti-cancer therapeutics in B-cell malignancies.Leukemia & lymphoma · 2013Article
- Saquinavir inhibits the malaria parasite's chloroquine resistance transporter.Antimicrobial agents and chemotherapy · 2012Article
- Comparative study of chloroquine and quinine on malaria rodents and their effects on the mouse testis.Asian Pacific journal of tropical biomedicine · 2012Article
- Synergy of the antiretroviral protease inhibitor indinavir and chloroquine against malaria parasites in vitro and in vivo.Parasitology research · 2011Article
- In vitro activity of antiretroviral drugs against Plasmodium falciparum.Antimicrobial agents and chemotherapy · 2011Article
- Antimalarial effects of human immunodeficiency virus protease inhibitors in rhesus macaques.Antimicrobial agents and chemotherapy · 2011Article
- HIV proteinase inhibitors target the Ddi1-like protein of Leishmania parasites.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2011Article
- Drug interactions in the treatment and chemoprophylaxis of malaria in HIV infected individuals in sub Saharan Africa.Current drug metabolism · 2011Review
- Drugs for malaria: something old, something new, something borrowed.F1000 biology reports · 2011Article
- HIV Protease Inhibitors: Effect on the Opportunistic Protozoan Parasites.The open medicinal chemistry journal · 2011Article
- Asexual and sexual stages of Plasmodium falciparum in Nigerian pregnant women attending antenatal booking clinic.Obstetric medicine · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The synergy of the activities between chloroquine and various human immunodeficiency virus protease inhibitors was investigated in chloroquine-resistant and -sensitive malaria parasites. In both in vitro and in vivo assay systems, ritonavir was found to be the most potent in potentiating the antimalarial action of chloroquine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.