ArticleWorld journal of gastroenterology2008
Severe acute pancreatitis in the elderly: etiology and clinical characteristics.
Article in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 73 citations in OpenAlex.
- Acute pancreatitis in elderly versus non-elderly population.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Global, regional, and national burdens of pancreatitis in adults aged ≥65 years from 1992 to 2021: A trends analysis using data from the 2021 Global Burden of Disease Study.Journal of intensive medicine · 2026Article
- Comparison of the Clinical Course, Management and Outcomes of Acute Pancreatitis in Aged and Young Patients.Biomedicines · 2026Review
- Epidemiology of acute pancreatitis: the influence of age and gender in a regional population.BMC gastroenterology · 2025Observational
- Article
- The Clinical Characteristics and Outcomes of Acute Pancreatitis Are Different in Elderly Patients: A Single-Center Study over a 6-Year Period.Journal of clinical medicine · 2024Article
- Impact of COVID-19 in individuals with and without pre-existent digestive disorders with a particular focus on elderly patients.World journal of gastroenterology · 2023Review
- Impact of comorbidities on hospital mortality in patients with acute pancreatitis: a population-based study of 110,021 patients.BMC gastroenterology · 2023Article
- Similarities and Differences Between Gerontal and Young Patients with Acute Pancreatitis: Evaluation of Clinical Characteristics and Outcomes.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2022Article
- Characteristics and clinical outcomes of patients over 80 years of age with acute pancreatitis.European geriatric medicine · 2022Article
- Outcome of acute pancreatitis in octogenarians: A retrospective study.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- The Clinical Characteristics of Acute Pancreatitis in Gerontal Patients: A Retrospective Study.Clinical interventions in aging · 2020Article
- Elderly persons with acute pancreatitis - specifics of the clinical course of the disease.Clinical interventions in aging · 2019Article
- Evaluation of Laboratory Findings and Mortality in Elderly Patients with Acute Biliary Pancreatitis.Sisli Etfal Hastanesi tip bulteni · 2018Article
- Update on the effect of age on acute pancreatitis morbidity: a retrospective, single-center study.Przeglad gastroenterologiczny · 2018Article
- Investigation of Geriatric Patients with Abdominal Pain Admitted to Emergency Department.Current gerontology and geriatrics research · 2018Article
- Obesity and pancreatitis.Current opinion in gastroenterology · 2017Review
- Article
- Association between red blood cell distribution width and acute pancreatitis.Medical science monitor : international medical journal of experimental and clinical research · 2014Article
- Gene expression profile of mouse white adipose tissue during inflammatory stress: age-dependent upregulation of major procoagulant factors.Aging cell · 2013Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the etiology and clinical characteristics of severe acute pancreatitis (SAP) in elderly patients (> or = 60 years of age).
methodsWe reviewed retrospectively all the SAP cases treated in Xuanwu Hospital in Beijing between 2000 and 2007.
resultsIn 169 patients with SAP, 94 were elderly and 16 died. Biliary and idiopathic etiologies were the first two causes that accounted for over 90% of SAP in the elderly. Biliary, hyperlipemic and alcoholic etiologies were the first three causes in the young. The proportion of co-morbidity of cholelithiasis, biliary infection, hypertension and coronary heart disease in the aged was significantly higher than that in their young partners. The scores of APACHE II and Ranson were also significantly higher in the elderly except the CT score. Organ failures were more common in the elderly, but the local pancreatic complications were not different between the two groups. Mortality of the aged was correlated with the severity of SAP, multiple co-morbidity and incidence of multiple organ dysfunction syndrome (MODS). MODS was the main cause of death.
conclusionThe etiology of SAP in the elderly is quite different from that in the young. Biliary and unknown factors are main causes in the aged. The elderly are subject to major organ failures but there is no difference in the occurrence of local pancreatic complications between the elderly and the young. It is crucial to monitor and improve the functions of major organs so as to prevent MODS in the aged with SAP.
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