Evidence map›Paper›PMID 18440333›Full record

ArticleAmerican heart journal2008

Gender disparity in cardiac procedures and medication use for acute myocardial infarction.

John T Nguyen, Alan K Berger, Sue Duval, Russell V Luepker

Open access · greenAbstract read
In one paragraph

Article in American heart journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 113 citations in OpenAlex.

  1. Trial
  2. Managing Postangiography Radial Artery Pseudoaneurysms: Systematic Review of the Published Literature.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Review
  3. Uncovering the gender health data gap.Cadernos de saude publica · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Observational
  12. Article
  13. Observational
  14. Observational
  15. The impact of gender on long-term mortality in patients with multivessel disease after primary percutaneous coronary intervention.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2015
    Article
  16. Review
  17. Article
  18. Article
  19. Mortality risk for women on chronic hemodialysis differs by age.Canadian journal of kidney health and disease · 2014
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

John T NguyenUniversity of Minnesota, Cardiovascular Division, Minneapolis, MN, USA.
Alan K Berger
Sue Duval
Russell V Luepker
University of Minnesota · US

Funding

COMMUNITY SURVEILLANCE OF CHD AND SUDDEN DEATH (MHS)R01HL065755 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LUEPKER, RUSSELL V · 2000 to 2004
$2.6M
Treatment of Acute Myocardial Infarction in the ElderlyK08HL083611 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERGER, ALAN KEITH · 2005 to 2009
$648k
NHLBI NIH HHS K08 HL083611NHLBI NIH HHS R01 HL065755
6 · The paper itself

Abstract

objectiveDetermine if gender bias is present in contemporary management of acute myocardial infarction (AMI).

backgroundDespite major advances in medicine, disparities in healthcare still persist. Previous studies on gender bias in the diagnosis and treatment of AMI are inconsistent and may not represent more contemporary practice. METHODS AND

resultsData were collected from the Minnesota Heart Survey, a population-based study of patients presenting with AMI in 2001-02. In-hospital diagnostic and therapeutic approaches were compared between women and men using logistic regression models. We identified 1242 women and 1378 men with an AMI defined by either positive cardiac biomarkers or ST-elevation on electrocardiogram. There were no differences in the prescription of aspirin, beta-blockers, ACE inhibitors or angiotensin receptor blockers. Women were 46% less likely than men to undergo investigative coronary angiography [OR = 0.54 (0.45-0.64)]. After accounting for confounders, women remained less likely to be referred for angiography [OR = 0.73 (0.57-0.94)]. Revascularization rates, were similar between women and men [OR = 0.96 (0.72-1.28)]. However, women were more likely to undergo PCI [OR = 1.41 (1.07-1.86)] whereas men were more likely to have coronary artery bypass grafting (CABG) [OR = 0.57 (0.39-0.84)]. When severity of coronary artery disease (CAD) was incorporated into the model, gender no longer influenced the modality of coronary revascularization.

conclusionsThere is no evidence of gender bias in the pharmacologic treatment of AMI. Evidence of gender bias persists in the referral of patients for coronary angiography but not in the subsequent use of coronary revascularization.

Indexed as

Myocardial RevascularizationPrejudiceAdultAgedAged, 80 and overBiomarkersCoronary AngiographyElectrocardiographyFemaleHealth SurveysHumansMaleMiddle AgedMyocardial InfarctionSex FactorsBiomarkers

Identifiers

PMID18440333
PMCPMC2709980
OpenAlexW2091948700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.