ArticleEmerging infectious diseases2008
Increasing hospitalizations and general practice prescriptions for community-onset staphylococcal disease, England.
Article in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2013Pooled it
- Efficacy and Safety of Ozenoxacin Cream for Treatment of Adult and Pediatric Patients With Impetigo: A Randomized Clinical Trial.JAMA dermatology · 2018Trial
- NVC-422 topical gel for the treatment of impetigo.International journal of clinical and experimental pathology · 2011Trial
- The dltC gene contributes to polyhexamethylene biguanide resistance inFrontiers in microbiology · 2025Article
- Purulent Skin and Soft Tissue Infections, Challenging the Practice of Incision and Drainage: A Scoping Review.Nursing research and practice · 2023Article
- Antibiotic Regimens and Associated Outcomes in Children Hospitalized With Staphylococcal Scalded Skin Syndrome.Journal of hospital medicine · 2021Article
- Variation in Diagnostic Test Use and Associated Outcomes in Staphylococcal Scalded Skin Syndrome at Children's Hospitals.Hospital pediatrics · 2018Article
- Staphylococcal Scalded Skin Syndrome in Child. A Case Report and a Review from Literature.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2016Article
- Understanding flucloxacillin prescribing trends and treatment non-response in UK primary care: a Clinical Practice Research Datalink (CPRD) study.The Journal of antimicrobial chemotherapy · 2016Article
- Evidence for increasing severity of community-onset boils and abscesses in UK General Practice.Epidemiology and infection · 2015Article
- Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management.Clinical microbiology reviews · 2015Review
- Nasal carriage of Staphylococcus aureus in Botucatu, Brazil: a population-based survey.PloS one · 2014Article
- Use of primary care data for detecting impetigo trends, United kingdom, 1995-2010.Emerging infectious diseases · 2013Article
- Evaluation of the national Cleanyourhands campaign to reduce Staphylococcus aureus bacteraemia and Clostridium difficile infection in hospitals in England and Wales by improved hand hygiene: four year, prospective, ecological, interrupted time series study.BMJ (Clinical research ed.) · 2012Article
- Increases in Australian cutaneous abscess hospitalisations: 1999-2008.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Article
- Staphylococcus aureus skin and soft tissue infections in primary healthcare in Denmark: a 12-year population-based study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2011Article
- Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic.Clinical microbiology reviews · 2010Review
- Increasing skin infections and Staphylococcus aureus complications in children, England, 1997-2006.Emerging infectious diseases · 2010Article
- Baseline factors predicting the duration of intravenous antibiotic therapy for cellulitis in an outpatient setting.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2010Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Rates of hospital-acquired staphylococcal infection increased throughout the 1990s; however, information is limited on trends in community-onset staphylococcal disease in the United Kingdom. We used Hospital Episode Statistics to describe trends in hospital admissions for community-onset staphylococcal disease and national general practice data to describe trends in community prescribing for staphylococcal disease. Hospital admission rates for staphyloccocal septicemia, staphylococcal pneumonia, staphylococcal scalded-skin syndrome, and impetigo increased >5-fold. Admission rates increased 3-fold for abscesses and cellulitis and 1.5-fold for bone and joint infections. In primary care settings during 1991-2006, floxacillin prescriptions increased 1.8-fold and fusidic acidprescriptions 2.5-fold. The increases were not matched by increases in admission rates for control conditions. We identified a previously undescribed but major increase in pathogenic community-onset staphylococcal disease over the past 15 years. These trends are of concern given the international emergence of invasive community-onset staphylococcal infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.