ArticleEmerging infectious diseases2008
Scale-up of multidrug-resistant tuberculosis laboratory services, Peru.
Article in Emerging infectious diseases, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Electronic laboratory system reduces errors in National Tuberculosis Program: a cluster randomized controlled trial.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2010Trial
- Full impact of laboratory information system requires direct use by clinical staff: cluster randomized controlled trial.Journal of the American Medical Informatics Association : JAMIATrial
- Evaluation of the postal service for referral of specimen of drug resistance tuberculosis in Amhara region, Ethiopia; mixed method.African health sciences · 2021Article
- The fourth national anti-tuberculosis drug resistance survey in Peru.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2020Article
- Improving outcomes for multi-drug-resistant tuberculosis in the Peruvian Amazon - a qualitative study exploring the experiences and perceptions of patients and healthcare professionals.BMC health services research · 2019Article
- Prevalence of pyrazinamide resistance and Wayne assay performance analysis in a tuberculosis cohort in Lima, Peru.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2017Article
- Chronic airflow obstruction after successful treatment of multidrug-resistant tuberculosis.ERJ open research · 2017Article
- Second line drug susceptibility testing to inform the treatment of rifampin-resistant tuberculosis: a quantitative perspective.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2017Review
- Article
- Impact of HIV on mortality among patients treated for tuberculosis in Lima, Peru: a prospective cohort study.BMC infectious diseases · 2016Article
- Time to initiation of multidrug-resistant tuberculosis treatment and its relation with outcome in a high incidence district in Lima, Peru.Tropical medicine & international health : TM & IH · 2015Article
- Salvage therapy for multidrug-resistant tuberculosis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2014Article
- Clinical characteristics, drug resistance, and treatment outcomes among tuberculosis patients with diabetes in Peru.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2013Article
- Managing and monitoring tuberculosis using web-based tools in combination with traditional approaches.Clinical epidemiology · 2013Review
- Impact of rapid drug susceptibility testing for tuberculosis: program experience in Lima, Peru.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2012Article
- Increasing access to the MDR-TB surveillance programme through a collaborative model in western Kenya.Tropical medicine & international health : TM & IH · 2012Article
- Improvement of tuberculosis laboratory capacity on Pemba Island, Zanzibar: a health cooperation project.PloS one · 2012Article
- The Innovative Socio-economic Interventions Against Tuberculosis (ISIAT) project: an operational assessment.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2011Article
- Weight variation over time and its association with tuberculosis treatment outcome: a longitudinal analysis.PloS one · 2011Article
- Targeted drug-resistance testing strategy for multidrug-resistant tuberculosis detection, Lima, Peru, 2005-2008.Emerging infectious diseases · 2011Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past 10 years, the Peruvian National Tuberculosis (TB) Program, the National Reference Laboratory (NRL), Socios en Salud, and US partners have worked to strengthen the national TB laboratory network to support treatment of multidrug-resistant TB. We review key lessons of this experience. The preparation phase involved establishing criteria for drug susceptibility testing (DST), selecting appropriate DST methods, projecting the quantity of DST and culture to ensure adequate supplies, creating biosafe laboratory facilities for DST, training laboratory personnel on methods, and validating DST methods at the NRL. Implementation involved training providers on DST indications, validating conventional and rapid first-line DST methods at district laboratories, and eliminating additional delays in specimen transport and result reporting. Monitoring included ongoing quality control and quality assurance procedures. Hurdles included logistics, coordinating with policy, competing interests, changing personnel, communications, and evaluation. Operational research guided laboratory scale-up and identified barriers to effective capacity building.
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