Trial reportJournal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Living well with stroke: design and methods for a randomized controlled trial of a psychosocial behavioral intervention for poststroke depression.
Trial report in Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychosocial/Behavioral Intervention in PSD
Psychosocial/Behavioral Intervention in Post-Stroke Depression (PSD)
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Pharmacological, non-invasive brain stimulation and psychological interventions, and their combination, for treating depression after stroke.The Cochrane database of systematic reviews · 2023Pooled it
- Pharmacological, psychological, and non-invasive brain stimulation interventions for treating depression after stroke.The Cochrane database of systematic reviews · 2020Pooled it
- Stroke liaison workers for stroke patients and carers: an individual patient data meta-analysis.The Cochrane database of systematic reviews · 2010Pooled it
- Randomized trial of telephone versus in-person delivery of a brief psychosocial intervention in post-stroke depression.BMC research notes · 2017Trial
- Communication and Low Mood (CALM): a randomized controlled trial of behavioural therapy for stroke patients with aphasia.Clinical rehabilitation · 2013Trial
- Response to psychosocial treatment in poststroke depression is associated with serotonin transporter polymorphisms.Stroke · 2011Trial
- Trial
- Stroke caregiver outcomes from the Telephone Assessment and Skill-Building Kit (TASK).Topics in stroke rehabilitationTrial
- Facilitators and barriers of life-space mobility in older adults with ischemic stroke: a descriptive qualitative study based on the COM-B.Frontiers in public health · 2026Article
- Life after stroke in Appalachia.International journal of nursing sciences · 2017Article
- Necessary and sufficient causes of participation post-stroke: practical and philosophical perspectives.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2014Article
- Comparison of two depression measures for predicting stroke outcomes.Journal of psychosomatic research · 2012Article
- Perceived wellbeing of patients one year post stroke in general practice--recommendations for quality aftercare.BMC neurology · 2011Article
- Factors Related to Continuation of Health Behaviours among Stroke Survivors.Journal of the Japanese Physical Therapy Association = Rigaku ryoho · 2011Article
- Gender and quality of life after cerebral stroke.Bosnian journal of basic medical sciences · 2010Article
- Stroke impact symptoms are associated with sleep-related impairment.Heart & lung : the journal of critical careArticle
- Reducing depressive or anxiety symptoms in post-stroke patients: Pilot trial of a constructive integrative psychosocial intervention.International journal of health sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDepression is a sufficiently common sequela of a completed stroke to warrant intervention to improve mood, social, and functional outcome. Pharmacologic trials suggest short-term mood improvement from antidepressant treatment but no studies to date have determined whether these short-term gains can be enhanced and extended by a brief psychosocial/behavioral intervention delivered by advanced practice nurses. In addition, drug trials have not reported on functional outcomes such as limitations in ability, limitations in participation, and overall quality of survival. This randomized controlled trial was designed to evaluate the short- and long-term efficacy of a new brief psychosocial/behavioral intervention adjunctive to antidepressant treatment in reducing poststroke depression and improving functional outcomes.
methodsA total of 101 survivors of ischemic stroke with poststroke depression were randomly assigned to receive a brief psychosocial/behavioral intervention plus antidepressant or usual care, including antidepressants.
resultsThe primary outcome was reduction in depressive symptom severity (Hamilton Depression Rating Scale) at 12 months after stroke. Secondary outcomes were reductions in limitations in activity (Barthel Index), reduction in limitation in participation, and overall stroke impact (Stroke Impact Scale) at 6, 12, and 24 months poststroke. Factors influencing best response to psychosocial intervention were also explored.
conclusionThis article provides detail on the design and treatment methods of this randomized trial in progress. Findings from this study provide important information regarding the long-term efficacy of such a behavioral intervention in reducing poststroke depression and subsequent impaired aspects of psychosocial and physical recovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.