Evidence map›Paper›PMID 18435840›Full record

SynthesisBMC pediatrics2008

Effectiveness of physical therapy interventions for children with cerebral palsy: a systematic review.

Heidi Anttila, Ilona Autti-Rämö, Jutta Suoranta, Marjukka Mäkelä, Antti Malmivaara

6 registry-linked trialsAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01633736 phase3unknown statusnot on this mapstarted 2011, after this paper: background citation

Targeted Hip Progressive Resistance Training to Improve Single Leg Balance and Walking in Children With Cerebral Palsy

TypeinterventionalSponsorUniversity of NottinghamRan2011 to 2013Enrolled20ConditionsCerebral PalsyArmsUsual care plus progresive resistance training
NCT02351596 naunknown statusnot on this mapstarted 2014, after this paper: background citation

The Effect of a 'Core Stability' Physiotherapy Group Intervention Programme on Balance in Ambulant Children With Cerebral Palsy: A Randomised Control Trial

TypeinterventionalSponsorRoyal College of Surgeons, IrelandRan2014 to 2015Enrolled48ConditionsCerebral PalsyArmsPhysiotherapy Core Stability Group Programme, Control Group
NCT05134259 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Role of Repetitive Transcranial Magnetic Stimulation in Spastic Hemiplegic Cerebral Palsy in a Sample of Egyptian Children

TypeinterventionalSponsorAl-Azhar UniversityRan2022 to 2022Enrolled60ConditionsCerebral PalsyArmsRepetitive Transcranial Magnetic Stimulation
NCT06450158 narecruitingnot on this mapstarted 2021, after this paper: background citation

Robot-assisted Hand Training to Induce Manual Functional Change and Cerebral Neural Plasticity in Children With Cerebral Palsy

TypeinterventionalSponsorCook Children's Health Care SystemRan2021 to 2029Enrolled80ConditionsCerebral PalsyArmsRobot (Amadeo)-assisted Training
NCT06887530 completednot on this mapstarted 2025, after this paper: background citation

Validity and Reliability of the Hand-10 Questionnaire in Children With Unilateral Cerebral Palsy

TypeobservationalSponsorGazi UniversityRan2025 to 2025Enrolled63ConditionsCerebral Palsy (CP), Hand FunctionsArmsHand-10 questionnaire and ABILHAND-kids questionnaire
NCT07547644 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of virtual reality training using wii fit on balance, gross motor function, and agility in children with cerebral palsy -a randomized controlled trial

TypeinterventionalSponsorZiauddin UniversityRan2026 to 2026Enrolled56ConditionsCerebral Palsy (CP), Virtual Reality, Balance, Gross Motor Function Classification System (GMFCS) Level I,IIArmsExperimental Group, control group
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Exercise interventions for cerebral palsy.The Cochrane database of systematic reviews · 2017
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Heidi AnttilaFinnish Office for Health Technology Assessment (FinOHTA), at the National Research and Development Centre for Welfare and Health (STAKES), PO Box 220, FIN-00531 Helsinki, Finland. heidi.anttila@stakes.fi
Ilona Autti-Rämö
Jutta Suoranta
Marjukka Mäkelä
Antti Malmivaara

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the effectiveness of physical therapy (PT) interventions on functioning in children with cerebral palsy (CP).

methodsA search was made in Medline, Cinahl, PEDro and the Cochrane library for the period 1990 to February 2007. Only randomized controlled trials (RCTs) on PT interventions in children with diagnosed CP were included. Two reviewers independently assessed the methodological quality and extracted the data. The outcomes measured in the trials were classified using the International Classification of Functioning, Disability and Health (ICF).

resultsTwenty-two trials were identified. Eight intervention categories were distinguished. Four trials were of high methodological quality. Moderate evidence of effectiveness was established for two intervention categories: effectiveness of upper extremity treatments on attained goals and active supination, and of prehensile hand treatment and neurodevelopmental therapy (NDT) or NDT twice a week on developmental status, and of constraint-induced therapy on amount and quality of hand use. Moderate evidence of ineffectiveness was found of strength training on walking speed and stride length. Conflicting evidence was found for strength training on gross motor function. For the other intervention categories the evidence was limited due to low methodological quality and the statistically insignificant results of the studies.

conclusionDue to limitations in methodological quality and variations in population, interventions and outcomes, mostly limited evidence on the effectiveness of most PT interventions is available through RCTs. Moderate evidence was found for some effectiveness of upper extremity training. Well-designed trials are needed especially for focused PT interventions.

Indexed as

Physical Therapy ModalitiesAdolescentCerebral PalsyChildChild, PreschoolHumansInfantRandomized Controlled Trials as TopicTreatment Outcome

Identifiers

PMID18435840
PMCPMC2390545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.