Trial reportJournal of dental research2008
Dental amalgam and psychosocial status: the New England Children's Amalgam Trial.
Trial report in Journal of dental research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Direct composite resin fillings versus amalgam fillings for permanent posterior teeth.The Cochrane database of systematic reviews · 2021Pooled it
- Dental composites and amalgam and physical development in children.Journal of dental research · 2012Trial
- Dental composite restorations and neuropsychological development in children: treatment level analysis from a randomized clinical trial.Neurotoxicology · 2012Trial
- Dental composite restorations and psychosocial function in children.Pediatrics · 2012Trial
- Dental sealants and flowable composite restorations and psychosocial, neuropsychological, and physical development in children.Pediatric dentistryTrial
- Awareness of Amalgam and Safe Removal Techniques Among Dentists in Turkey: A Cross-Sectional Study.Oral health & preventive dentistry · 2025Article
- Is Dental Amalgam a Higher Risk Factor rather than Resin-Based Restorations for Systemic Conditions? A Systematic Review.Materials (Basel, Switzerland) · 2021Review
- Clinical Effects of Mercury in Conservative Dentistry: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Randomized Controlled Trials.International journal of dentistry · 2020Review
- Determination of Highly Sensitive Biological Cell Model Systems to Screen BPA-Related Health Hazards Using Pathway Studio.International journal of molecular sciences · 2017Article
- Changes in urinary bisphenol A concentrations associated with placement of dental composite restorations in children and adolescents.Journal of the American Dental Association (1939) · 2016Article
- Bisphenol A Release: Survey of the Composition of Dental Composite Resins.The open dentistry journal · 2016Article
- The decision to repair or replace a defective restoration is affected by who placed the original restoration: findings from the National Dental PBRN.Journal of dentistry · 2014Article
- Human exposure and health effects of inorganic and elemental mercury.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2012Review
- Restorative material and other tooth-specific variables associated with the decision to repair or replace defective restorations: findings from The Dental PBRN.Journal of dentistry · 2012Article
- The dental amalgam toxicity fear: a myth or actuality.Toxicology international · 2012Article
- Bisphenol A and related compounds in dental materials.Pediatrics · 2010Review
- Nephrotoxicity, neurotoxicity, and mercury exposure among children with and without dental amalgam fillings.International journal of hygiene and environmental health · 2009Article
- Absorbed Dose and Image Quality of X-Ray Diagnostics in Composite and Amalgam Dental Restorations.Journal of medical physicsArticle
- Mercury exposure levels in children with dental amalgam fillings.International journal of clinical pediatric dentistryArticle
- Knowledge, Attitude, and Behavior of Restorative, Orthodontic, and Pediatric Departments' Members toward Bisphenol A Dental Exposures.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
High-dose exposures to elemental mercury vapor cause emotional dysfunction, but it is uncertain whether the levels of exposure that result from having dental amalgam restorations do so. As part of the New England Children's Amalgam Trial, a randomized trial involving 6- to 10-year-old children, we evaluated the hypothesis that restoration of caries using dental amalgam resulted in worse psychosocial outcomes than restoration using mercury-free composite resin. The primary outcome was the parent-completed Child Behavior Checklist. The secondary outcome was children's self-reports using the Behavior Assessment System for Children. Children's psychosocial status was evaluated in relation to three indices of mercury exposure: treatment assignment, surface-years of amalgam, and urinary mercury excretion. All significant associations favored the amalgam group. No evidence was found that exposure to mercury from dental amalgams was associated with adverse psychosocial outcomes over the five-year period following initial placement of amalgams.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.