Evidence map›Paper›PMID 18434571›Full record

ReviewJournal of dental research2008

Mechanisms of tooth eruption and orthodontic tooth movement.

G E Wise, G J King

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of dental research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07587567 (Determination of Risk Factors for Eruption Disorders in the Primary and Permanent Dentition), which is not on this map. Cited by 218 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
218citing papers in PubMed, 8 pooled it
10.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07587567 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Determination of Risk Factors for Eruption Disorders in the Primary and Permanent Dentition

TypeinterventionalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2026 to 2030Enrolled50ConditionsTooth Eruption DisorderArmsPTH1R gene analysis
3 · Its place in the literature

Who cites it

218 citing papers in PubMed, 8 syntheses or guidelines pooled it, 574 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Hounsfield unit change in root and alveolar bone during canine retraction.American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · 2015
    Trial
  10. Trial
  11. Review
  12. Mechanical control in dental and jaw morphogenesis and remodeling.International journal of oral science · 2026
    Review
  13. Article
  14. Primary tooth emergence in young children is associated with a stress biomarker.Journal of developmental origins of health and disease · 2026
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

158 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

G E WiseDepartment of Comparative Biomedical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA. gwise@vetmed.lsu.edu
G J King
Louisiana State University · USUniversity of Washington · US

Funding

MOLECULAR BASIS OF TOOTH ERUPTIONR01DE008911 · NIDCR · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI YAO, SHAOMIAN · 1991 to 2012
$3.9M
NIDCR NIH HHS DE08911-16NIDCR NIH HHS R01 DE008911
6 · The paper itself

Abstract

Teeth move through alveolar bone, whether through the normal process of tooth eruption or by strains generated by orthodontic appliances. Both eruption and orthodontics accomplish this feat through similar fundamental biological processes, osteoclastogenesis and osteogenesis, but there are differences that make their mechanisms unique. A better appreciation of the molecular and cellular events that regulate osteoclastogenesis and osteogenesis in eruption and orthodontics is not only central to our understanding of how these processes occur, but also is needed for ultimate development of the means to control them. Possible future studies in these areas are also discussed, with particular emphasis on translation of fundamental knowledge to improve dental treatments.

Indexed as

Alveolar ProcessBone RemodelingBone ResorptionHumansOsteoclastsTooth EruptionTooth MigrationTooth Movement Techniques

Identifiers

PMID18434571
PMCPMC2387248
OpenAlexW1964611109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.