ReviewMethods in enzymology2008
Analysis of nitric oxide-dependent antimicrobial actions in macrophages and mice.
Review in Methods in enzymology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Mesenteric macrophage-monocyte circuit controls systemic inflammation during enteric bacterial infection.The Journal of experimental medicine · 2026Article
- The expression of fungal CotH, human glucose-regulated protein 78 (GRP78), and predicted miRNAs in macrophages and diabetic mice infected withMicrobiology spectrum · 2025Article
- MyD88-mediated signaling in intestinal fibroblasts regulates macrophage antimicrobial defense and prevents dysbiosis in the gut.Cell reports · 2025Article
- Survival ofMicroorganisms · 2022Article
- Purification, Chemical Characterization and Immunomodulatory Activity of a Sulfated Polysaccharide from Marine Brown AlgaeMarine drugs · 2022Article
- Role of nitric oxide in regulating epidermal permeability barrier function.Experimental dermatology · 2022Review
- Direct and Indirect Inhibition ofmBio · 2020Article
- Autophagy Induction by a Small Molecule InhibitsAntimicrobial agents and chemotherapy · 2019Article
- MAV_4644 Interaction with the Host Cathepsin Z ProtectsMicroorganisms · 2019Article
- Zinc-dependent substrate-level phosphorylation powers Salmonella growth under nitrosative stress of the innate host response.PLoS pathogens · 2018Article
- Tim-3 exacerbates kidney ischaemia/reperfusion injury through the TLR-4/NF-κB signalling pathway and an NLR-C4 inflammasome activation.Clinical and experimental immunology · 2018Article
- Myeloid Differentiation Factor 88 and Interleukin-1R1 Signaling Contribute to Resistance to Coccidioides immitis.Infection and immunity · 2018Article
- Proinflammatory MG-63 cells response infection with Enterococcus faecalis cps2 evaluated by the expression of TLR-2, IL-1β, and iNOS mRNA.BMC research notes · 2017Article
- Article
- Neither dectin-2 nor the mannose receptor is required for resistance to Coccidioides immitis in mice.Infection and immunity · 2014Article
- The intracellular environment of human macrophages that produce nitric oxide promotes growth of mycobacteria.Infection and immunity · 2013Article
- Article
- Hemoglobin: a nitric-oxide dioxygenase.Scientifica · 2012Review
- A comprehensive study on the role of the Yersinia pestis virulence markers in an animal model of pneumonic plague.Folia microbiologica · 2011Article
- DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine.PLoS pathogens · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Nitric oxide (NO*) is a critical component of mammalian host defense that is produced in macrophages and other cells comprising the innate immune system. Isolated mammalian macrophages have been utilized to measure the kinetics of NO production and to demonstrate NO-related antimicrobial actions. Some microorganisms possess enzymes to detoxify nitrogen oxides, and mutant strains lacking these enzymes can be used to demonstrate the importance of these mechanisms for intracellular bacterial survival. This chapter describes techniques with which to analyze the antimicrobial actions of nitric oxide in murine and human macrophages and in laboratory mice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.