Evidence map›Paper›PMID 18432753›Full record

ArticleCurrent protocols in immunology2001

Animal models for the analysis of immune responses to leishmaniasis.

D L Sacks, P C Melby

Open access · greenAbstract read
In one paragraph

Article in Current protocols in immunology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 132 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

D L SacksNational Institute of Allergy & Infectious, Diseases, Bethesda, Maryland, USA.
P C Melby
National Institute of Allergy and Infectious Diseases · USThe University of Texas Health Science Center at San Antonio · US

Funding

IMMUNE REGULATION AND VACCINE DEVELOPMENT IN LEISHMANIASISZ01AI000494 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI SACKS, DAVID · 1987 to 2008
$1.5M
Intramural NIH HHS Z01 AI000494
6 · The paper itself

Abstract

This unit focuses on the murine model of cutaneous leishmaniasis and models of visceral leishmaniasis in mice and hamsters. Each basic protocol describes the methods used to inoculate parasites and to evaluate infections with regard to lesion progression and visceralization, and quantification of parasite load. Five support protocols are provided; two for the growth and isolation of metacyclic promastigotes from in vitro culture, one for isolation of tissue amastigotes from infected animals, one for cryopreservation of parasites, and one for the preparation of blood agar plates for quantitation of parasite numbers in infected tissue.

Indexed as

Disease Models, AnimalLeishmaniaAnimalsCulture MediaErythrocytesLeishmaniasis, CutaneousLife Cycle StagesMiceCulture Media

Identifiers

PMID18432753
PMCPMC4363783
OpenAlexW2149429062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.