ArticleCurrent protocols in immunology2001
Schistosomiasis.
Article in Current protocols in immunology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 56 citations in OpenAlex.
- Chemical inhibition of α-mannosidase inFrontiers in parasitology · 2026Article
- Insights into the epidemiology, pathogenesis, and differential diagnosis of schistosomiasis.European journal of microbiology & immunology · 2024Review
- The stage- and sex-specific transcriptome of the human parasite Schistosoma mansoni.Scientific data · 2023Article
- Study of the behavior of snails intermediate hosts ofHeliyon · 2022Article
- Experimental Schistosoma japonicum-induced pulmonary hypertension.PLoS neglected tropical diseases · 2022Article
- Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae.PLoS neglected tropical diseases · 2021Article
- The esophageal gland mediates host immune evasion by the human parasiteProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Identification of annotated bioactive molecules that impair motility of the blood fluke Schistosoma mansoni.International journal for parasitology. Drugs and drug resistance · 2020Article
- Chlorination of Schistosoma mansoni cercariae.PLoS neglected tropical diseases · 2020Article
- Aquatic macrophytes and macroinvertebrate predators affect densities of snail hosts and local production of schistosome cercariae that cause human schistosomiasis.PLoS neglected tropical diseases · 2020Article
- Myricetin Possesses Anthelmintic Activity and Attenuates Hepatic FibrosisFrontiers in immunology · 2020Article
- A rotifer-derived paralytic compound prevents transmission of schistosomiasis to a mammalian host.PLoS biology · 2019Article
- In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination.PLoS neglected tropical diseases · 2019Article
- Octopamine signaling in the metazoan pathogenDisease models & mechanisms · 2018Article
- Isolation and Characterization of Extracellular Vesicles from Adult Schistosoma japonicum.Journal of visualized experiments : JoVE · 2018Article
- Molecular characterization of serine protease inhibitor isoform 3, SmSPI, from Schistosoma mansoni.Parasitology research · 2016Article
- Identification of Antigenic Glycans from Schistosoma mansoni by Using a Shotgun Egg Glycan Microarray.Infection and immunity · 2016Article
- Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis.Mucosal immunology · 2016Article
- The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development.PLoS neglected tropical diseases · 2015Article
- A constitutively active G protein-coupled acetylcholine receptor regulates motility of larval Schistosoma mansoni.Molecular and biochemical parasitology · 2015Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The trematode parasites in the family Schistosomatidae (phylum Platyhelminthes) infect a wide range of vertebrates. Three species of the genus Schistosoma are of major medical importance. This unit deals exclusively with the parasite Schistosoma mansoni, which is the species most frequently maintained in the laboratory. Among the far-ranging investigations in the immunology of schistosomiasis are studies in vaccine development, immunopathology of granulomatous inflammation and fibrosis, eosinophil function, and in vivo regulation of T(H)1 and T(H)2 responses. This unit describes maintenance and collection procedures for various stages of the schistosome that have immunologic interest, including infection of mice with cercariae, collection of cercariae, preparation of in vitro-derived schistosomules and in vivo-derived schistosomules, and collection of adult worms and eggs. Included also are techniques for preparing soluble egg antigen (SEA), one of the more commonly used schistosome antigenic preparations. A discussion is given of the basic steps that are important in maintaining the snail intermediate host, and infecting the snails with schistosome miracidia. The unit deals exclusively with the parasite Schistosoma mansoni, which is the species most frequently maintained in the laboratory. Since part of the life cycle of all schistosomes involves a snail host, a description of proper maintenance for the snails is provided. Often, problems in experiments can be traced back to improper snail and parasite maintenance, or lack of attention to detail during mammalian exposure to the infective stage (cercaria) of the parasite.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.