ArticleImmunogenetics2008
Genomic location and characterisation of nonclassical MHC class I genes in cattle.
Article in Immunogenetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Bighorn sheep T2T genome assembly reveals differences in immune genes: a potential cause of high morbidity due to respiratory pathogens.bioRxiv : the preprint server for biology · 2025Article
- Expression of MHC I Isoforms in Bovine Placentomes: Impact of Cloning.Veterinary sciences · 2025Article
- Detection of potential functional variants based on systems-biology: the case of feed efficiency in beef cattle.BMC genomics · 2022Article
- Spatial distribution and incidence of bovine neonatal pancytopenia in Bavaria, Germany.BMC veterinary research · 2020Article
- Genetic and epigenetic regulation of major histocompatibility complex class I gene expression in bovine trophoblast cells.American journal of reproductive immunology (New York, N.Y. : 1989) · 2018Article
- Bovine Neonatal Pancytopenia-Associated Alloantibodies Recognize Individual Bovine Leukocyte Antigen 1 Alleles.Frontiers in immunology · 2018Article
- A novel RNAseq-assisted method for MHC class I genotyping in a non-model species applied to a lethal vaccination-induced alloimmune disease.BMC genomics · 2016Article
- A comprehensive mapping of the structure and gene organisation in the sheep MHC class I region.BMC genomics · 2015Article
- The assembly and characterisation of two structurally distinct cattle MHC class I haplotypes point to the mechanisms driving diversity.Immunogenetics · 2015Article
- Constraints on haplotype structure and variable gene frequencies suggest a functional hierarchy within cattle MHC class I.Immunogenetics · 2012Article
- Cattle MHC nomenclature: is it possible to assign sequences to discrete class I genes?Immunogenetics · 2012Article
- Vaccine-induced antibodies linked to bovine neonatal pancytopenia (BNP) recognize cattle major histocompatibility complex class I (MHC I).Veterinary research · 2011Article
- Transcription variants of SLA-7, a swine non classical MHC class I gene.BMC proceedings · 2011Article
- Analysis of MHC class I genes across horse MHC haplotypes.Immunogenetics · 2010Article
- Genomic location and characterisation of MIC genes in cattle.Immunogenetics · 2008Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
The cattle major histocompatibility complex (MHC) region contains a variable number of classical class I genes encoding polymorphic, ubiquitously expressed molecules with a role in antigen presentation. Class I cDNA sequences have previously been reported that are thought to derive from putative nonclassical class I genes. We have located four nonclassical class I genes within the cattle genome; three are close to the MIC genes, and one is close to the classical class I genes. The genomic position relative to anchor genes is very similar to the arrangement reported in the pig MHC region. We have designed gene-specific oligonucleotide primers with which to investigate the presence of these genes in distinct and well-defined MHC haplotypes and to assess transcription in different cell types. Analysis and comparison of all sequences allows an assessment of allelic variation in each case. Partial characterisation gives an indication of the possible role and likely importance of each of these genes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.