Evidence map›Paper›PMID 18430958›Full record

ArticleGenetics2008

Visual mutations reveal opposing effects of illumination on arousal in Drosophila.

Yuzhong Cheng, Howard A Nash

Abstract read
In one paragraph

Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuzhong ChengLaboratory of Molecular Biology, National Institutes of Mental Health, Bethesda, Maryland 20892-3736, USA.
Howard A Nash

Funding

Genetic Neurobiology Of DrosophilaZIAMH002228 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WHITE, BENJAMIN H · 2009 to 2013
$4.8M
GENETIC NEUROBIOLOGY OF DROSOPHILAZ01MH002228 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI NASH, HOWARD A · 1986 to 2008
$4.1M
Intramural NIH HHS
6 · The paper itself

Abstract

The effect of illumination on alertness can be assessed by comparing the efficacy of an anesthetic under light vs. dark conditions. Results from such tests on wild-type flies and visual mutants demonstrate that, surprisingly, light has both positive and negative influences on arousal. These dual effects may explain aspects of the fly's daily activity and have potential clinical implications.

Indexed as

LightAnesthesiaAnimalsArousalDose-Response Relationship, RadiationDrosophila melanogasterMutationVision, Ocular

Identifiers

PMID18430958
PMCPMC2323825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.