Evidence map›Paper›PMID 18428830›Full record

ArticleCurrent protocols in nucleic acid chemistry2001

Probing RNA folding pathways by RNA fingerprinting.

S A Woodson

Abstract read
In one paragraph

Article in Current protocols in nucleic acid chemistry, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. TRMT1L-catalyzed mCell reports · 2025
    Article
  2. TRMT1L-catalyzed mbioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

S A WoodsonJohns Hopkins University, Baltimore, Maryland, USA.

Funding

TIME RESOLVED HYDROXYL RADICAL FOOTPRINTING OF RNAR01GM060819 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI WOODSON, SARAH A. · 1999 to 2019
$6.1M
Role of Exon Structure in Splicing of Group I IntronsR01GM046686 · NIGMS · UNIVERSITY OF MARYLAND COLLEGE PK CAMPUS · PI WOODSON, SARAH A. · 1992 to 2014
$4.0M
NIGMS NIH HHS R01 GM046686NIGMS NIH HHS R01 GM060819
6 · The paper itself

Abstract

This unit provides protocols for using native polyacrylamide gel electrophoresis to distinguish folding and unfolding conformers of RNA. It is useful for studying conformers that can exchange in a period of minutes or seconds, and that are thus difficult to study by solution-based methods. Conformers that have been separated and immobilized in the gel matrix can be used to studying catalytic activity with or without being eluted from the gel. The method can be applied to a wide varied of catalytic RNAs and RNA-protein complexes.

Indexed as

Nucleic Acid ConformationBiochemistryCatalysisDNA-Directed RNA PolymerasesElectrophoresis, Gel, Two-DimensionalElectrophoresis, Polyacrylamide GelPhosphorus RadioisotopesRNARNA PrecursorsRNA SplicingViral Proteinsbacteriophage T7 RNA polymeraseDNA-Directed RNA PolymerasesPhosphorus RadioisotopesRNARNA PrecursorsRNA primersViral Proteins

Identifiers

PMID18428830
PMCPMC5538802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.