ArticleJournal of translational medicine2008
Practical aspects in the management of hypokalemic periodic paralysis.
Article in Journal of translational medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 4 registered trials, which are not on this map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Single-dose Potassium Supplementation in ADHD Patients With Lidocaine Ineffectiveness
Assessing the Frequency of Lidocaine Ineffectiveness in the General Population vs. Males With ADHD, and Females With ADHD, With or Without PMS
Reliability Testing of a Non-invasive, Pain-free, Taste-based Assessment Approach to Lidocaine Effectiveness
Prevalence of Lidocaine Ineffectiveness in Those With Hard-to-treat ADHD
Who cites it
25 citing papers in PubMed, 74 citations in OpenAlex.
- Hypokalemic periodic paralysis triggered by exertion and cold exposure in a resource-limited Ethiopian setting: a case report.Journal of medical case reports · 2026Article
- Lifestyle and dietary measures in Periodic Paralyses.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2026Review
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- Exploring self-management of diet and physical activity inJournal of neuromuscular diseases · 2025Article
- Sudden Tetraplegia from Hypokalaemic Periodic Paralysis Due to Cacna1s Mutation: Should Genetic Testing be Performed More Often?European journal of case reports in internal medicine · 2025Article
- Diagnosis, management and outcomes of primary hypokalemic periodic paralysis during pregnancy.Obstetric medicine · 2024Article
- Article
- Article
- Muscle channelopathies: A review.Annals of the Child Neurology Society · 2023Review
- Hypokalemic periodic paralysis in a teenage boy after an intense period of exercise: A rare case report.Clinical case reports · 2023Article
- Article
- A Successful Obstetric Outcome in a Woman With Familial Hypokalemic Periodic Paralysis: Challenges in Management.Cureus · 2022Article
- Acute flaccid paralysis in Indonesian adult due to suspected familial hypokalemia paralysis: A rare case.Annals of medicine and surgery (2012) · 2022Article
- Hypokalaemia with Guillain-Barré syndrome: a diagnostic and therapeutic challenge.BMJ case reports · 2022Article
- Atypical Fracture of Femur in Association with Familial Hypokalemic Periodic Paralysis: A Case Report.Journal of orthopaedic case reports · 2021Article
- The Role of Nutrition and Physical Activity as Trigger Factors of Paralytic Attacks in Primary Periodic Paralysis.Journal of neuromuscular diseases · 2021Review
- Thyrotoxic periodic paralysis: A retrospective, observational study from India.The Indian journal of medical research · 2020Observational
- A Case of Thiazide-induced Hypokalemic Paralysis.Clinical practice and cases in emergency medicine · 2019Article
- Clinical and Etiological Spectrum of Hypokalemic Periodic Paralysis in a Tertiary Care Hospital in Pakistan.Cureus · 2019Article
- Treatment and management of neuromuscular channelopathies.Current treatment options in neurology · 2014Article
Corrections and comments
- Erratum issuedDosage error in article text
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Management considerations in hypokalemic periodic paralysis include accurate diagnosis, potassium dosage for acute attacks, choice of diuretic for prophylaxis, identification of triggers, creating a safe physical environment, peri-operative measures, and issues in pregnancy. A positive genetic test in the context of symptoms is the gold standard for diagnosis. Potassium chloride is the favored potassium salt given at 0.5-1.0 mEq/kg for acute attacks. The oral route is favored, but if necessary, a mannitol solvent can be used for intravenous administration. Avoidance of or potassium prophylaxis for common triggers, such as rest after exercise, high carbohydrate meals, and sodium, can prevent attacks. Chronically, acetazolamide, dichlorphenamide, or potassium-sparing diuretics decrease attack frequency and severity but are of little value acutely. Potassium, water, and a telephone should always be at a patient's bedside, regardless of the presence of weakness. Perioperatively, the patient's clinical status should be checked frequently. Firm data on the management of periodic paralysis during pregnancy is lacking. Patient support can be found at http://www.periodicparalysis.org.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.