Evidence map›Paper›PMID 18425285›Full record

ArticleSao Paulo medical journal = Revista paulista de medicina2008

Divergences in antihypertensive therapy in special situations in nephrology.

Marcelo Montebello Lemos, Alessandra Coelho Pedrosa, Alze Pereira Tavares, Miguel Angelo Góes, Sérgio Antônio Draibe, Ricardo Sesso

Open access · diamondAbstract read
In one paragraph

Article in Sao Paulo medical journal = Revista paulista de medicina, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marcelo Montebello LemosDiscipline of Nephrology, Universidade Federal de São Paulo, São Paulo, Brazil. mmontebello@uol.com.br
Alessandra Coelho Pedrosa
Alze Pereira Tavares
Miguel Angelo Góes
Sérgio Antônio Draibe
Ricardo Sesso
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CONTEXT AND

objectiveThe choice of an antihypertensive drug is based on several criteria and specific situations give rise to doubt and controversy. The aim here was to evaluate physicians approaches towards treatment with antihypertensive agents in specific situations. DESIGN AND

settingCross-sectional study, at Universidade Federal de São Paulo, São Paulo.

methodsA questionnaire was applied during a nephrology meeting to evaluate individual approaches towards each hypothetical clinical situation. The questionnaire consisted of five multiple-choice questions (clinical cases) concerning controversial aspects of antihypertensive therapy.

resultsA total of 165 questionnaires were analyzed. Most participants were nephrologists (93.2%). There was a preference for angiotensin-converting enzyme (ACE) inhibitors in at least two of the cases. Only 57.2% of the physicians were correct in choosing beta-blockers as the first-line drugs for patients with ischemic coronary disease. Moreover, 66.2% chose ACE inhibitors as the first-line drugs for patients with chronic kidney disease and proteinuria. About 5% of the physicians did not follow the current recommendations for the use of ACE inhibitors in diabetic patients with microalbuminuria. The most controversial question concerned the first-line drug for advanced chronic kidney disease. Most physicians were correct in choosing calcium channel blockers and avoiding ACE inhibitors in renovascular hypertension in the case of a patient with a single functioning kidney.

conclusionsMost physicians adopted the correct approach, but some had an alternative strategy for the same situations that was not based on evidence.

Indexed as

Guideline AdherenceAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCalcium Channel BlockersClinical CompetenceDrug PrescriptionsEvidence-Based MedicineHumansHypertensionKidney Failure, ChronicNephrologyPractice Guidelines as TopicPractice Patterns, Physicians'Renal Artery ObstructionAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCalcium Channel Blockers

Identifiers

PMID18425285
PMCPMC11020520
OpenAlexW2034318043

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.