ReviewAdvanced drug delivery reviews2008
Combinatorial and rational approaches to polymer synthesis for medicine.
Review in Advanced drug delivery reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Mapping Biomaterial Complexity by Machine Learning.Tissue engineering. Part A · 2024Review
- Polymer designChemical science · 2024Article
- Chemically Tuned Intracellular Gene Delivery by Core-Shell Nanoparticles: Effects of Proton Buffering, Acid Degradability, and Membrane Disruption.ChemMedChem · 2022Article
- Automation and data-driven design of polymer therapeutics.Advanced drug delivery reviews · 2021Review
- High-Throughput Preparation of Antibacterial Polymers from Natural Product Derivatives via the Hantzsch Reaction.iScience · 2020Article
- Stiffness can mediate balance between hydrodynamic forces and avidity to impact the targeting of flexible polymeric nanoparticles in flow.Nanoscale · 2019Article
- Nanoparticle transport phenomena in confined flows.Advances in heat transfer · 2019Article
- An Oxygen-Tolerant PET-RAFT Polymerization for Screening Structure-Activity Relationships.Angewandte Chemie (International ed. in English) · 2018Article
- Platinum covalent shell cross-linked micelles designed to deliver doxorubicin for synergistic combination cancer therapy.International journal of nanomedicine · 2017Article
- Investigating the Synergistic Effects of Combined Modified Alginates on Macrophage Phenotype.Polymers · 2016Article
- Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors.Royal Society open science · 2016Article
- Modular and orthogonal synthesis of hybrid polymers and networks.Chemical communications (Cambridge, England) · 2015Review
- Molecular design and evaluation of biodegradable polymers using a statistical approach.Journal of materials science. Materials in medicine · 2013Article
- Image-guided nanosystems for targeted delivery in cancer therapy.Current medicinal chemistry · 2012Review
- Identification of osteoconductive and biodegradable polymers from a combinatorial polymer library.Journal of biomedical materials research. Part A · 2010Article
- Bioinspired materials for controlling stem cell fate.Accounts of chemical research · 2010Review
- A novel high-throughput cell-based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery.Biotechnology and bioengineering · 2009Article
- Inhibition of protein-protein interactions with low molecular weight compounds.Current trends in medicinal chemistry · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
High-throughput, combinatorial methods have revolutionized small molecule synthesis and drug discovery. By combining automation, miniaturization, and parallel synthesis techniques, large collections of new compounds have been synthesized and screened. It is becoming increasingly clear that these same approaches can also assist the discovery and development of novel biomaterials for medicine. This review examines combinatorial and rational polymer synthesis for medical applications, including stem cell engineering and nucleic acid drug delivery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.