Evidence map›Paper›PMID 18421293›Full record

SynthesisMolecular psychiatry2008

Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement.

A E Baum, M Hamshere, E Green, S Cichon, M Rietschel, M M Noethen, N Craddock, F J McMahon

Abstract readLetterMeta-Analysis
In one paragraph

Synthesis in Molecular psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Non-replication of association for six polymorphisms from meta-analysis of genome-wide association studies of Parkinson's disease: large-scale collaborative study.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2010
    Pooled it
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. The Role of Genetics in Bipolar Disorder.Current topics in behavioral neurosciences · 2021
    Article
  11. Review
  12. Article
  13. Ankyrins: Roles in synaptic biology and pathology.Molecular and cellular neurosciences · 2018
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2015
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A E Baum
M Hamshere
E Green
S Cichon
M Rietschel
M M Noethen
N Craddock
F J McMahon

Funding

Mapping genes that contribute to bipolar disorderZIAMH002810 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MCMAHON, FRANCIS J · 2009 to 2025
$31.2M
Mapping genes that contribute to bipolar disorderZ01MH002810 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MCMAHON, FRANCIS J · 2003 to 2008
$2.0M
A Collaborative Genomic Study of Bipolar DisorderZ01MH002842 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MCMAHON, FRANCIS J · 2004 to 2008
$1.2M
Genetic Linkage and Association in Bipolar DisorderZ01MH002843 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MCMAHON, FRANCIS J · 2004 to 2008
$1.1M
A Collaborative Genomic Study of Bipolar DisorderZIAMH002842 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI MCMAHON, FRANCIS J · 2009 to 2010
$1.0M
Intramural NIH HHS Z01 MH002810Intramural NIH HHS Z01 MH002842Intramural NIH HHS Z01 MH002843Medical Research Council G9810900Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Polymorphism, Single NucleotideAnimalsBipolar DisorderCase-Control StudiesCation Transport ProteinsCell Adhesion MoleculesGenotypeGermanyHumansOligonucleotide Array Sequence AnalysisQuantitative Trait LociRatsResearch DesignSampling StudiesSpecies SpecificityUnited StatesCation Transport ProteinsCell Adhesion MoleculesJAM3 protein, humanSLC39A3 protein, human

Identifiers

PMID18421293
PMCPMC2435183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.