Evidence map›Paper›PMID 18418706›Full record

ArticleVirus genes2008

Genomic sequence analysis of a granulovirus isolated from the Old World bollworm, Helicoverpa armigera.

Robert L Harrison, Holly J R Popham

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Virus genes, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

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  17. Baculovirus: molecular insights on their diversity and conservation.International journal of evolutionary biology · 2011
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robert L HarrisonInvasive Insect Biocontrol and Behavior Laboratory, Plant Sciences Institute, USDA, Agricultural Research Service, Building 011A, Room 214, BARC-W, 10300 Baltimore Avenue, Beltsville, MD 20705, USA. Robert.L.Harrison@ars.usda.gov
Holly J R Popham
Agricultural Research Service · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome of a granulovirus isolated from the Old World bollworm, Helicoverpa armigera, was completely sequenced. The size of the Helicoverpa armigera granulovirus (HearGV) genome is 169,794 nt containing 179 open reading frames (ORFs), making it the second largest baculovirus genome analyzed to date. The genomes of HearGV and the Xestia c-nigrum GV (XecnGV) exhibit extensive sequence similarity and co-linearity, with both genomes containing the same nine homologous regions (hrs) with conserved structure and locations and sharing 167 open reading frames (ORFs). Phylogenetic inference and pairwise analysis of Kimura-2-parameter nucleotide distances for the lef-8, lef-9, and granulin genes indicate that HearGV is part of a cluster of granuloviruses typified by XecnGV. The HearGV genome contains all 62 ORFs found in common among other fully sequenced lepidopteran baculovirus genomes, as well as seven ORFs unique to HearGV. In addition, HearGV and XecnGV genomes share 20 ORFs not found among other baculovirus genomes sequenced to date. In addition to possessing ten ORFs with sequence similarity to baculovirus repeated ORFs (bro), the HearGV genome contains members of two other gene families with homologues in ascovirus, nucleopolyhedrovirus, and entomopoxvirus genomes. Alignment of the HearGV and XecnGV genome sequences revealed that HearGV is missing approximately 16.6 kbp of XecnGV-homologous sequence and contains approximately 8.2 kbp of sequence not found in the XecnGV genome.

Indexed as

Genome, ViralAnimalsDNA, ViralGranulovirusMolecular Sequence DataMothsMultigene FamilyOpen Reading FramesPhylogenySequence AnalysisSequence HomologyViral ProteinsDNA, ViralViral Proteins

Identifiers

PMID18418706
OpenAlexW2018780974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.