ArticleCerebellum (London, England)2008
The role of cerebellar genes in pathology of autism and schizophrenia.
Article in Cerebellum (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 68 citations in OpenAlex.
- Shared Genetic Determinants of Schizophrenia and Autism Spectrum Disorder Implicate Opposite Risk Patterns: A Genome-Wide Analysis of Common Variants.Schizophrenia bulletin · 2024Article
- Viral-mediated inflammation by Poly I:C induces the chemokine CCL5 in NK cells and its receptors CCR1 and CCR5 in microglia in the neonatal rat cerebellum.NeuroImmune pharmacology and therapeutics · 2024Article
- DISC1 and reelin interact to alter cognition, inhibition, and neurogenesis in a novel mouse model of schizophrenia.Frontiers in cellular neuroscience · 2023Article
- How Does Maternal Separation Affect the Cerebellum? Assessment of the Oxidative Metabolic Activity and Expression of the c-Fos Protein in Male and Female Rats.Cerebellum (London, England) · 2020Article
- Schizophrenia and Influenza at the Centenary of the 1918-1919 Spanish Influenza Pandemic: Mechanisms of Psychosis Risk.Frontiers in psychiatry · 2020Review
- Evidence that inflammation promotes estradiol synthesis in human cerebellum during early childhood.Translational psychiatry · 2019Article
- The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum.Journal of neuroscience research · 2017Article
- Differential motor and prefrontal cerebello-cortical network development: Evidence from multimodal neuroimaging.NeuroImage · 2016Article
- DNA microarray unravels rapid changes in transcriptome of MK-801 treated rat brain.World journal of biological chemistry · 2015Article
- MRI analysis of cerebellar and vestibular developmental phenotypes in Gbx2 conditional knockout mice.Magnetic resonance in medicine · 2013Article
- The involvement of Reelin in neurodevelopmental disorders.Neuropharmacology · 2013Review
- Viral infection, inflammation and schizophrenia.Progress in neuro-psychopharmacology & biological psychiatry · 2013Review
- Is autism a disease of the cerebellum? An integration of clinical and pre-clinical research.Frontiers in systems neuroscience · 2013Article
- Transient mGlu5R inhibition enhances the survival of granule cell precursors in the neonatal cerebellum.Neuroscience · 2012Article
- Murine adult neural progenitor cells alter their proliferative behavior and gene expression after the activation of Toll-like-receptor 3.European journal of microbiology & immunology · 2012Article
- Neonatal behavioral changes in rats with gestational exposure to lipopolysaccharide: a prenatal infection model for developmental neuropsychiatric disorders.Schizophrenia bulletin · 2012Article
- Reduced ventricular proliferation in the foetal cortex following maternal inflammation in the mouse.Brain : a journal of neurology · 2011Article
- Use of zebrafish as a model to understand mechanisms of addiction and complex neurobehavioral phenotypes.Neurobiology of disease · 2010Review
- Cerebellar lingula thickness as a novel risk factor for alcohol and drug abuse.Cerebellum (London, England) · 2010Article
- Past, present and future therapeutics for cerebellar ataxias.Current neuropharmacology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Schizophrenia and autism are neurodevelopmental diseases that have genetic as well as environmental etiologies. Both disorders have been associated with prenatal viral infection. Brain imaging and postmortem studies have found alterations in the structure of the cerebellum as well as changes in gene expression. Our laboratory has developed an animal model using prenatal infection of mice with human influenza virus that has demonstrated changes in behavior, pharmacology, structure, and gene expression in the brains of exposed offspring. In the current communication we describe altered expression of cerebellar genes associated with development of brain disorder in a mouse model for schizophrenia and autism and correlate these changes with those involved in the pathology of these two disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.