ArticleIndian journal of ophthalmology
Investigative modalities in infectious keratitis.
Article in Indian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Reverse endothelial scraping technique for refractory deep infectious keratitis: Novel surgical technique and outcome evaluation.Indian journal of ophthalmology · 2026Article
- Predicting the causative agent in microbial keratitis: the role of anterior segment optical coherence tomography-a cross-sectional analysis.International ophthalmology · 2025Article
- Rabbit Corneal Wound Treatment Using Small Intestinal Submucosa (SIS) and Platelet Rich Plasma (PRP) Scaffold.Archives of Razi Institute · 2025Article
- A Convolutional Neural Network Using Anterior Segment Photos for Infectious Keratitis Identification.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Microbiological culture versus 16S/18S rRNA gene PCR-sanger sequencing for infectious keratitis: a three-arm, diagnostic cross-sectional study.Frontiers in medicine · 2024Article
- Urgent unmet needs in the care of bacterial keratitis: An evidence-based synthesis.The ocular surface · 2023Article
- Post-Keratoplasty Infectious Keratitis Caused by Elizabethkingia meningoseptica.The American journal of case reports · 2023Article
- Photoactivated Chromophore Corneal Collagen Cross-Linking for Infectious Keratitis (PACK-CXL)-A Comprehensive Review of Diagnostic and Prognostic Factors Involved in Therapeutic Indications and Contraindications.Journal of personalized medicine · 2022Review
- Biological Staining and Culturing in Infectious Keratitis: Controversy in Clinical Utility.Medical hypothesis, discovery & innovation ophthalmology journal · 2019Review
- Corneal biopsy for diagnosis of recalcitrant microbial keratitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018Article
- Virulence genome analysis ofGenomics data · 2017Article
- Reevaluation of an Acanthamoeba Molecular Diagnostic Algorithm following an Atypical Case of Amoebic Keratitis.Journal of clinical microbiology · 2015Article
- Microbial keratitis following vegetative matter injury.International ophthalmology · 2013Article
- A management dilemma: infectious keratitis associated with soft contact lens use and dubious treatment compliance.Case reports in medicine · 2010Article
- Laboratory diagnosis of amoebic keratitis: comparison of four diagnostic methods for different types of clinical specimens.Journal of clinical microbiology · 2009Article
- A retrospective study of fungal corneal ulcers in the South sharqiyah region in oman.Sultan Qaboos University medical journal · 2009Article
- Diagnosis of infections caused by pathogenic free-living amoebae.Interdisciplinary perspectives on infectious diseases · 2009Article
- Recent trends: Medical management of infectious keratitis.Oman journal of ophthalmologyReview
- Investigative modalities in infectious keratitis.Indian journal of ophthalmologyArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Standard recommended guidelines for diagnosis of infectious keratitis do exist. Based on an extensive Medline literature search, the various investigative modalities available for aiding the diagnosis of microbial keratitis have been reviewed and described briefly. Preferred practice patterns have been outlined and the importance of routine pre-treatment cultures in the primary management of infectious keratitis has been highlighted. Corneal scraping, tear samples and corneal biopsy are few of the specimens needed to carry out the investigative procedures for diagnosis and for initiating therapy in cases of microbial keratitis. In bacterial, fungal and amoebic keratitis, microscopic examination of smears is essential for rapid diagnosis. Potassium hydroxide (KOH) wet mount, Gram's stain and Giemsa stain are widely used and are important for clinicians to start empirical therapy before microbial culture results are available. The usefulness of performing corneal cultures in all cases of suspected infectious keratitis has been well established. In cases of suspected viral keratitis, therapy can be initiated on clinical judgment alone. If a viral culture is needed, scrapings should directly be inoculated into the viral transport media. In vivo confocal microscopy is a useful adjunct to slit lamp bio-microscopy for supplementing diagnosis in most cases and establishing early diagnosis in many cases of non-responding fungal and amoebic keratitis. This is a non-invasive, high resolution technique which allows rapid detection of Acanthamoeba cysts and trophozoites and fungal hyphae in the cornea long before laboratory cultures give conclusive results. Other new modalities for detection of microbial keratitis include molecular diagnostic techniques like polymerase chain reaction, and genetic finger printing by pulsed field gel electrophoresis.
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18417821PMC2636118W2054511433What OpenQuestion holds
Registered trials
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