ArticleJournal of virology2008
Basolateral entry and release of New and Old World arenaviruses from human airway epithelia.
Article in Journal of virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- Powassan Viruses Spread Cell to Cell during Direct Isolation fromJournal of virology · 2022Article
- Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses.The Journal of experimental medicine · 2020Article
- Analysis of the Cell Type-Dependence on the Arenavirus Z-Mediated Virus-Like Particle Production.Frontiers in microbiology · 2020Article
- Article
- Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells.Virology journal · 2018Article
- Mammarenaviral Infection Is Dependent on Directional Exposure to and Release from Polarized Intestinal Epithelia.Viruses · 2018Article
- Polarized Entry of Human Parechoviruses in the Airway Epithelium.Frontiers in cellular and infection microbiology · 2018Article
- Lassa Virus Cell Entry via Dystroglycan Involves an Unusual Pathway of Macropinocytosis.Journal of virology · 2016Article
- Mutations in the cytoplasmic domain of the Newcastle disease virus fusion protein confer hyperfusogenic phenotypes modulating viral replication and pathogenicity.Journal of virology · 2013Article
- Nipah virus entry and egress from polarized epithelial cells.Journal of virology · 2013Article
- Advanced vaccine candidates for Lassa fever.Viruses · 2012Review
- Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Tyrosine residues in the cytoplasmic domains affect sorting and fusion activity of the Nipah virus glycoproteins in polarized epithelial cells.Journal of virology · 2010Article
- Viral protein determinants of Lassa virus entry and release from polarized epithelial cells.Journal of virology · 2010Article
- The nucleoprotein of lymphocytic choriomeningitis virus facilitates spread of persistent infection through stabilization of the keratin network.Journal of virology · 2009Article
- Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates.Vaccine · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Transmission of arenaviruses from rodent hosts to humans is generally thought to occur through inhalation or ingestion of dust or droplets containing viral particles. Here we demonstrate that two identified arenavirus receptors, alpha-dystroglycan (alpha-DG) and transferrin receptor 1 (TfR1), are expressed in polarized human airway epithelia. Lymphocytic choriomeningitis virus strains with high or low alpha-DG affinity and Junin virus, which binds TfR1, efficiently infected polarized epithelia only when applied to the basolateral surface or when injury compromised tight junction integrity. Viral egress from infected epithelia exhibited basolateral polarity. This study demonstrates that respiratory entry of arenaviruses occurs via basolateral receptors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.