ReviewCurrent allergy and asthma reports2008
The mold conundrum in chronic rhinosinusitis: where do we stand today?
Review in Current allergy and asthma reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 33 citations in OpenAlex.
- AWMF mold guideline "Medical clinical diagnostics for indoor mold exposure" - Update 2023 AWMF Register No. 161/001.Allergologie select · 2024Article
- Article
- Allergic Aspergillus Rhinosinusitis.Journal of fungi (Basel, Switzerland) · 2016Review
- Pathology of Fungal Rhinosinusitis: A Review.Head and neck pathology · 2016Review
- The Etiology and Pathogenesis of Chronic Rhinosinusitis: a Review of Current Hypotheses.Current allergy and asthma reports · 2015Review
- Fungal extracts detected in eosinophilic chronic rhinosinusitis induced cytokines from the nasal polyp cells.The Laryngoscope · 2014Article
- Fungi, β-glucan, and bacteria in nasal lavage of greenhouse workers and their relation to occupational exposure.The Annals of occupational hygiene · 2013Article
- Role of fungi in the pathophysiology of chronic rhinosinusitis: an update.Current allergy and asthma reports · 2013Review
- Fungal rhinosinusitis: a retrospective microbiologic and pathologic review of 400 patients at a single university medical center.International journal of otolaryngology · 2012Article
- Mold and human health: separating the wheat from the chaff.Clinical reviews in allergy & immunology · 2010Review
- Perspectives on the etiology of chronic rhinosinusitis.Current opinion in otolaryngology & head and neck surgery · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic rhinosinusitis (CRS) is an inflammatory disorder affecting the nose and paranasal sinuses. Although bacteria have long been implicated as pathogens in most forms of CRS, fungi may be responsible for some forms. Several recent studies demonstrated that, under optimal conditions, fungi can be identified in the nose and paranasal sinuses of nearly every individual (including all CRS patients). An aberrant immune response to these ubiquitous fungi has been suggested to explain the development of CRS in some individuals. Several mechanisms requiring additional research, including adequate controls, have been proposed and are reviewed in this article. Although preliminary trials suggested that CRS signs and symptoms improve upon treatment with topical and oral antifungal agents, several double-blind, placebo-controlled trials demonstrated the contrary. In the absence of convincing immunologic data and evidence of clinical improvement upon therapy with antifungal agents, the case against fungi remains unproven.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.