ReviewCurrent HIV/AIDS reports2008
Regulatory T cells in HIV infection: who's suppressing what?
Review in Current HIV/AIDS reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Delayed gastrointestinal-associated lymphoid tissue reconstitution in duodenum compared with rectum in HIV-infected patients initiating antiretroviral therapy.AIDS (London, England) · 2019Trial
- Spatially visualized single-cell pathology of highly multiplexed protein profiles in health and disease.Communications biology · 2021Article
- The immune pathogenesis of immune reconstitution inflammatory syndrome associated with highly active antiretroviral therapy in AIDS.AIDS research and human retroviruses · 2014Article
- HIV-1 immunopathogenesis in humanized mouse models.Cellular & molecular immunology · 2012Review
- Increased frequency of regulatory T cells accompanies increased immune activation in rectal mucosae of HIV-positive noncontrollers.Journal of virology · 2011Article
- Regulatory T cells in HIV immunotherapy.HIV therapy · 2010Article
- FOXP3 expression is upregulated in CD4T cells in progressive HIV-1 infection and is a marker of disease severity.PloS one · 2010Article
- Article
- Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis.Science China. Life sciences · 2010Review
- Effector mechanisms in HIV-1 infected elite controllers: highly active immune responses?Antiviral research · 2010Review
- Immunopathogenesis of asymptomatic chronic HIV Infection: the calm before the storm.Current opinion in HIV and AIDS · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of regulatory T cells (Treg) in HIV pathogenesis is not fully elucidated. Persistent antigens, such as HIV, are believed to promote the expansion and activation of antigen-specific Treg, and several reports have described beneficial and detrimental roles for Treg in HIV pathogenesis. These apparently contradictory observations may arise from imprecision in enumerating Treg and the lack of definition of Treg subsets. New markers allowing more precise identification and purification of Treg for functional studies have been described recently, and these may open avenues for efficient isolation of pure, homogenous populations of human Treg.
Indexed as
Identifiers
18417031What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.