Trial reportLipids in health and disease2008
Raisins and additional walking have distinct effects on plasma lipids and inflammatory cytokines.
Trial report in Lipids in health and disease, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Fructose-containing food sources and blood pressure: A systematic review and meta-analysis of controlled feeding trials.PloS one · 2023Pooled it
- Pooled it
- Dried Fruit Intake and Cancer: A Systematic Review of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Food sources of fructose-containing sugars and glycaemic control: systematic review and meta-analysis of controlled intervention studies.BMJ (Clinical research ed.) · 2018Pooled it
- Effect of Grape Polyphenols on Blood Pressure: A Meta-Analysis of Randomized Controlled Trials.PloS one · 2015Pooled it
- The effect of black seed raisin on some cardiovascular risk factors, serum malondialdehyde, and total antioxidant capacity in hyperlipidemic patients: a randomized controlled trials.Irish journal of medical science · 2022Trial
- Dried fruit consumption and cardiometabolic health: a randomised crossover trial.The British journal of nutrition · 2020Trial
- Açai pulp supplementation as a nutritional strategy to prevent oxidative damage, improve oxidative status, and modulate blood lactate of male cyclists.European journal of nutrition · 2020Trial
- Relationship Between FODMAP Diet and Irritable Bowel Syndrome: A Mendelian Randomization Study.Food science & nutrition · 2025Article
- Causal effects of cardiovascular health on five epigenetic clocks.Clinical epigenetics · 2024Article
- Association between dried fruit intake and kidney function: research from univariate and multivariate Mendelian randomized studies.Frontiers in nutrition · 2024Article
- Causal associations between dried fruit intake and cardiovascular disease: A Mendelian randomization study.Frontiers in cardiovascular medicine · 2023Article
- Dried fruit intake causally protects against low back pain: A Mendelian randomization study.Frontiers in nutrition · 2023Article
- Temporal Pattern of Neuroinflammation Associated with a Low Glycemic Index Diet in the 5xFAD Mouse Model of Alzheimer's Disease.Molecular neurobiology · 2022Article
- Association of a pro-inflammatory diet with type 2 diabetes and hypertension: results from the Ravansar non-communicable diseases cohort study.Archives of public health = Archives belges de sante publique · 2022Article
- A systematic comprehensive longitudinal evaluation of dietary factors associated with acute myocardial infarction and fatal coronary heart disease.Nature communications · 2020Article
- Effect of grape polyphenols on selected inflammatory mediators: A systematic review and meta-analysis randomized clinical trials.EXCLI journal · 2020Article
- Is Eating Raisins Healthy?Nutrients · 2019Review
- Review
- Evaluation of the Anti-Inflammatory Activity of Raisins (Vitis vinifera L.) in Human Gastric Epithelial Cells: A Comparative Study.International journal of molecular sciences · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRaisins are a significant source of dietary fiber and polyphenols, which may reduce cardiovascular disease (CVD) risk by affecting lipoprotein metabolism and inflammation. Walking represents a low intensity exercise intervention that may also reduce CVD risk. The purpose of this study was to determine the effects of consuming raisins, increasing steps walked, or a combination of these interventions on blood pressure, plasma lipids, glucose, insulin and inflammatory cytokines.
resultsThirty-four men and postmenopausal women were matched for weight and gender and randomly assigned to consume 1 cup raisins/d (RAISIN), increase the amount of steps walked/d (WALK) or a combination of both interventions (RAISINS + WALK). The subjects completed a 2 wk run-in period, followed by a 6 wk intervention. Systolic blood pressure was reduced for all subjects (P = 0.008). Plasma total cholesterol was decreased by 9.4% for all subjects (P < 0.005), which was explained by a 13.7% reduction in plasma LDL cholesterol (LDL-C) (P < 0.001). Plasma triglycerides (TG) concentrations were decreased by 19.5% for WALK (P < 0.05 for group effect). Plasma TNF-alpha was decreased from 3.5 ng/L to 2.1 ng/L for RAISIN (P < 0.025 for time and group x time effect). All subjects had a reduction in plasma sICAM-1 (P < 0.01).
conclusionThis research shows that simple lifestyle modifications such as adding raisins to the diet or increasing steps walked have distinct beneficial effects on CVD risk.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.