ReviewExpert review of neurotherapeutics2008
Pituitary tumors in childhood: update of diagnosis, treatment and molecular genetics.
Review in Expert review of neurotherapeutics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 138 citations in OpenAlex.
- Higher surgical cure of pediatric gigantism with endoscopic endonasal surgery: case series and review of the literature.Pituitary · 2026Review
- Sex differences in the clinical presentation, management and long-term outcomes of pituitary tumors in children and adolescents.Pituitary · 2026Review
- Pediatric pituitary adenomas: clinical features, treatment strategies, and management challenges.Endocrine · 2025Article
- Review
- Clinical and therapeutic outcomes of pediatric pituitary adenomas: a single pituitary center experience.Endocrine · 2024Article
- An update on, and genetics of refractory adenomas of childhood.Pituitary · 2023Review
- Non-functioning pituitary microadenoma in children and adolescents: Is follow-up with diagnostic imaging necessary?Endocrine · 2023Article
- Sellar and parasellar lesions in the transition age: a retrospective Italian multi-centre study.Journal of endocrinological investigation · 2023Article
- Alternative Lengthening of Telomeres (ALT) and Telomerase Reverse Transcriptase Promoter Methylation in Recurrent Adult and Primary Pediatric Pituitary Neuroendocrine Tumors.Endocrine pathology · 2022Article
- Review
- Supratentorial Pediatric Midline Tumors and Tumor-like Lesions: Clinical Spectrum, Natural History and Treatment Options.Children (Basel, Switzerland) · 2022Review
- Characteristics and overall survival in pediatric versus adult pituitary adenoma: a National Cancer Database analysis.Pituitary · 2021Article
- Molecular characterization of DICER1-mutated pituitary blastoma.Acta neuropathologica · 2021Article
- The epidemiology and management patterns of pediatric pituitary tumors in the United States.Pituitary · 2021Article
- Dealing With Brain MRI Findings in Pediatric Patients With Endocrinological Conditions: Less Is More?Frontiers in endocrinology · 2021Review
- Article
- Aggressive pituitary tumors in the young and elderly.Reviews in endocrine & metabolic disorders · 2020Review
- A middle cerebral artery ischemic stroke occurring in a child with a large prolactinoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Transsphenoidal surgery for pituitary adenomas in pediatric patients: a multicentric retrospective study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Pediatric pituitary adenomas.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 4 countries.
Funding
Abstract
Pituitary tumors are rare in childhood and adolescence, with a reported prevalence of up to one per 1 million children. Only 2-6% of surgically treated pituitary tumors occur in children. Although pituitary tumors in children are almost never malignant and hormonal secretion is rare, these tumors may result in significant morbidity. Tumors within the pituitary fossa are mainly of two types: craniopharyngiomas and adenomas. Craniopharyngiomas cause symptoms by compressing normal pituitary, causing hormonal deficiencies and producing mass effects on surrounding tissues and the brain; adenomas produce a variety of hormonal conditions such as hyperprolactinemia, Cushing disease and acromegaly or gigantism. Little is known about the genetic causes of sporadic lesions, which comprise the majority of pituitary tumors, but in children, more frequently than in adults, pituitary tumors may be a manifestation of genetic conditions such as multiple endocrine neoplasia type 1, Carney complex, familial isolated pituitary adenoma and McCune-Albright syndrome. The study of pituitary tumorigenesis in the context of these genetic syndromes has advanced our knowledge of the molecular basis of pituitary tumors and may lead to new therapeutic developments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.